Inhibitory Effects of Ethionine, an Analogue of Methionine, on Wool Growth

    PJ Reis, DA Tunks
    TLDR Ethionine significantly inhibits wool growth in sheep but not hair growth in mice or rats.
    The study investigated the effects of ethionine, a methionine analogue, on wool growth in sheep and hair growth in mice and rats. Sheep received varying amounts of DL-, L-, or D-ethionine either through continuous infusion over 2 days or a single injection. Sucking mice and rats in their first hair growth cycle were given subcutaneous injections of DL-ethionine at different doses. The results indicated that ethionine inhibited wool growth in sheep and hair growth in mice and rats, demonstrating its potential as a growth inhibitor in these species.
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