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The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

New effective scar treatments are urgently needed due to the current options' limited success.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Estrogen therapy can reduce skin aging but has cancer risks.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Skin can be cooled quickly and safely during laser treatments to protect it without affecting deeper layers.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Certain bacteria and fungi are linked to healthy scalps and dandruff, suggesting that the scalp's microbial balance affects its health.

The transscrotal testosterone patch normalizes hormone levels in men with AIDS and weight loss but does not improve weight, body mass, or quality of life.

Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.

Most patients with chronic kidney disease have skin problems, which get worse as the disease progresses, and dialysis doesn't greatly reduce these issues.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.