September 2019 in “Journal of Investigative Dermatology” This clinical trial found that Sandalore® 1% significantly reduced hair shedding and increased hair volume and anagen hair follicles in women with telogen effluvium compared to placebo.
January 2026 in “Regenerative Biomaterials” This study highlights that hydrogel formulations unexpectedly prolonged healing in trials, pointing to a need for design based on detailed pathophysiological insights rather than empirical methods, and suggests technologies like AI materials optimization and 3D bioprinting to aid their clinical use for cancer survivors.
February 2026 in “Frontiers in Medicine” This study suggests that combining LMWHA solution and HCO might improve mild to moderate urinary incontinence in women with GSM, potentially offering benefits over HA therapy alone, but further research is needed.
16 citations
,
March 1981 in “PubMed” This study found that minoxidil significantly reduced blood pressure in patients with intractable hypertension and was generally well-tolerated, although fluid retention and hirsutism posed some challenges.
6 citations
,
May 2024 in “Macromolecular Bioscience” This study synthesized a temperature-sensitive hydrogel with strong antibacterial capabilities against S. aureus and E. coli, demonstrated via in vitro and in vivo tests, suggesting potential for antibiotic-free clinical applications when activated by near-infrared light.
March 2024 in “Biochimica et biophysica acta. Molecular basis of disease” This study found that deferoxamine may protect against sensorineural hearing loss by reducing oxidative stress-induced hair cell death through iron chelation and activation of the Nrf2 signaling pathway in lab models.
19 citations
,
June 1999 in “Steroids” This study found that compound 10 inhibited testosterone conversion to DHT in hamster flank organs and seminal vesicles, whereas compound 11's inhibitory effect varied with dose, linked to halogen electronegativity differences.
83 citations
,
September 2021 in “Advanced functional materials” This study introduced a multifunctional DNA hydrogel dressing that may enhance wound healing by promoting tissue regeneration, nerve repair, and immune response in diabetic infectious wounds.
2 citations
,
November 2022 in “International journal of research - granthaalayah” This study found that energy emitted by a hydrocolloid-based wound dressing fragment can penetrate glass and delay the evaporation of a Potassium Ferricyanide solution around a human hair follicle in vitro.
8 citations
,
January 1991 in “Soviet physics. Doklady” This article suggests that testosterone therapy might be considered if other treatments fail, but emphasizes discussing potential risks and benefits with patients before prescribing.
6 citations
,
December 2022 in “Journal of Materials Chemistry B” This study found that a bilayer wound dressing capable of releasing hydrogen sulfide promoted wound healing in rats by reducing inflammation, enhancing vascularization, and facilitating hair follicle regeneration.
1 citations
,
December 2022 in “Indian pediatrics/Indian Pediatrics” A toddler who accidentally swallowed hair growth medicine experienced serious heart-related side effects but recovered after hospital treatment.
August 2025 in “Cermin Dunia Kedokteran” This article discusses Human Metapneumovirus (HMPV) and highlights the need for continued research, noting that while supportive treatments exist, no vaccines or specific therapies are currently available.
65 citations
,
October 2015 in “Acta Biomaterialia” This study found that using a pH-sensitive layered double hydroxide nanocarrier to deliver etoposide significantly reduced liver toxicity and enhanced the drug’s effectiveness in targeting and suppressing non-small cell lung cancer.
December 2024 in “Jurnal Mandala Pharmacon Indonesia” In this study, high-dose oral administration of Ramania leaf ethanol extract in Wistar rats resulted in no significant acute toxicity symptoms, though gastric ulcers and hair loss were observed. The extract is classified as non-toxic under specified guidelines, with an LD50 greater than 5000 mg/kg.
6 citations
,
October 1979 in “Chest” This study found that minoxidil significantly reduces systemic blood pressure and vascular resistance in patients with hypertension, but does not alter pulmonary vascular resistance or exacerbate pulmonary hypertension.
June 2021 in “International Journal of Ayurvedic Medicine” This study found that humulen, a phytoconstituent of Cyperus Rotundus Linn., showed the highest binding affinity in molecular docking with the 5 α reductase enzyme, suggesting potential anti-androgenic effects for hirsutism treatment.
52 citations
,
May 2011 in “APOPTOSIS” In this study, cisplatin was found to induce cell death in human hair follicle cells through hydroxyl radical generation and Bcl-2 down-regulation, suggesting potential strategies for preventing chemotherapy-induced alopecia.
In this study, researchers successfully synthesized a rigid 3a-arylhexahydropentalene-1,6-dione from the easily accessible starting material cyclopent-2-en-1-one, highlighting a structural motif common in natural products and pharmaceuticals.
118 citations
,
May 2015 in “European journal of pharmaceutics and biopharmaceutics” This study found that the pH-sensitive hydrogel HECHA13, containing isoliquiritigenin, effectively inhibited the growth of Propionibacterium acnes and showed promise for transdermal delivery in acne treatment.
March 2024 in “Journal of Microbiology and Biotechnology” This study suggests that phloroglucinol may enhance anagen signaling and reduce oxidative stress-induced damage in human dermal papilla cells, offering a potential therapy for hair loss.
July 2024 in “Journal of the American Academy of Dermatology” Low-dose oral minoxidil is generally safe for hypertensive patients with hair loss.
7 citations
,
June 2025 in “Nano Energy” This study reports that triboelectro-responsive DNA hydrogels, enhanced with conductive polymers and triboelectric stimulation, effectively accelerate wound healing and exhibit strong anti-bacterial and anti-inflammatory properties, achieving 99.8% closure of bacterium-infected diabetic wounds in 14 days.
July 2026 in “Dermatology Reports” In this pilot study, a medical device gel with hyaluronic acid and hydrogen peroxide showed promising safety and clinical performance for treating folliculitis in adults, reducing lesion count and improving severity scores and quality of life over 8 weeks.
50 citations
,
September 1975 in “American Heart Journal” Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.
4 citations
,
December 2024 in “JAAD Case Reports” This review discusses previously reported cases of drug-associated hidradenitis suppurativa linked to various immunomodulating medications but reports no new clinical results.
19 citations
,
July 1983 in “American Journal of Kidney Diseases” Minoxidil lowers blood pressure in kids with kidney issues, but use carefully due to side effects.
4 citations
,
December 2023 in “Advanced science” This study found that injectable gelatin/metal/tea polyphenol double nanonetworks significantly accelerated wound healing in diabetic wounds by enhancing cell migration and providing anti-inflammatory and antioxidant properties, without detectable cytotoxicity in tests.
August 2025 in “Archives of Dermatological Research” This systematic review and meta-analysis suggest that oral minoxidil may be a safer and more effective option for children with hair disorders and refractory hypertension, though further large-scale trials are needed.
July 2026 in “Aesthetic Plastic Surgery” This pilot study found that intradermal 10% glucose combined with non-cross-linked hyaluronic acid improved hair density and diameter more than hyaluronic acid alone in adults with androgenetic alopecia, with no serious adverse events.