TLDR Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.
This 47-year-old document discusses the use of minoxidil in patients with severe hypertension who have not responded to conventional drugs. The study found that minoxidil was effective in controlling blood pressure in these patients, even in those with renal insufficiency. However, some patients experienced fluid retention and edema as a side effect of the drug. The study also found that concomitant drug therapy was necessary to block the reflex cardiac effects of the vasodilator. Overall, the study suggests that minoxidil may be a useful option for patients with severe hypertension who have failed to respond to other treatments.
180 citations,
July 1973 in “The New England Journal of Medicine” Minoxidil effectively lowers blood pressure with few side effects.
100 citations,
March 1973 in “American Journal of Cardiology” Minoxidil effectively lowers blood pressure without major side effects.
90 citations,
May 1972 in “Clinical Pharmacology & Therapeutics” Minoxidil quickly leaves blood, turns into urine metabolites, and has lasting blood pressure-lowering effects.
January 2023 in “Dermatologic Therapy” The new 5% minoxidil foam is as effective and safe as Rogaine® for treating hair loss in Chinese men.
16 citations,
January 1995 in “Skin Pharmacology and Physiology” SEPA™ enhances the effectiveness of minoxidil in stimulating hair growth, working faster and better than Rogaine® TS, with no significant side effects.
6 citations,
July 2005 in “Farmaco” A quick and simple method was created to identify minoxidil in hair-growth products using micellar electrokinetic capillary chromatography.
1 citations,
May 2014 in “Hair transplant forum international” Rogaine can stop hair loss in women, and other treatments like certain pills, light therapy, and special shampoos may also work.
April 2011 in “The FASEB Journal” Topical Minoxidil is cost-effective for managing baldness but requires continuous use.
January 2011 in “The Internet Journal of Pharmacology” Minoxidil is cost-effective for regrowing hair on the scalp's top but not the front, requiring ongoing use.
