52 citations,
September 2018 in “International Journal of Molecular Sciences” Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.
5 citations,
March 2017 in “Laser Physics Letters” Different scalp imaging methods are important for studying hair and scalp health and require more volunteers for better evaluation.
3 citations,
November 1999 in “Journal of Cutaneous Medicine and Surgery” Examining scalp biopsies in different ways helps better diagnose hair loss types.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” 17β-estradiol may help hair growth by increasing cannabinoid receptor type 1.
36 citations,
January 2015 in “Dermatology” Bimatoprost was found to be safer and more effective than mometasone furoate for treating scalp hair loss.
23 citations,
June 2012 in “Molecular Biology Reports” VEGF stimulates hair cell growth and increases growth receptor levels through a specific signaling pathway.
19 citations,
April 2010 in “Journal of Dermatological Treatment” Partial hair follicle extraction can effectively double the number of hair follicles for transplants, with most surviving and growing normally after a year.
9 citations,
August 2014 in “The Journal of Dermatology” Scalp areas that look normal in people with hair loss may still show signs of disease under a microscope.
5 citations,
September 1998 in “Atlas of the oral and maxillofacial surgery clinics of North America” Hair transplantation and micrografting, used for baldness, involve moving hair follicles from hair-rich to bald areas, requiring careful procedure and post-care for success.
1 citations,
July 2018 in “Elsevier eBooks” Triple horizontal scalp biopsies are 98% accurate in diagnosing hair loss, better than single biopsies.
309 citations,
May 1993 in “Journal of The American Academy of Dermatology” Horizontal scalp biopsy sections effectively diagnose and predict MPAA, with follicular density and inflammation impacting hair regrowth.
208 citations,
December 2003 in “Journal of Investigative Dermatology” Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.
179 citations,
April 2012 in “Nature Communications” Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.
46 citations,
September 2014 in “Tissue engineering. Part A” Researchers created hair-inducing human cell clusters using a 3D culture method.
42 citations,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
15 citations,
February 2003 in “British Journal of Dermatology” The study suggests computer-assisted analysis of scalp biopsies could improve hair loss diagnosis but needs more validation.
9 citations,
January 1995 in “Aesthetic Plastic Surgery” New suturing technique with wider intervals and shallow stitches helps prevent scalp scars and promotes hair growth.
5 citations,
September 2012 in “Springer eBooks” Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.
3 citations,
April 2016 in “Wound Repair and Regeneration” Researchers successfully transplanted hair follicles in mice, which survived well and helped in wound healing.
3 citations,
May 1980 in “American Journal of Nursing” Scalp tourniquets did not significantly prevent hair loss from chemotherapy.
759 citations,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
305 citations,
February 2007 in “Hormone and metabolic research” Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.
236 citations,
July 2001 in “Trends in Molecular Medicine” Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
185 citations,
August 2005 in “Autoimmunity Reviews” Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.
65 citations,
October 1999 in “Journal of The American Academy of Dermatology” Finasteride effectively reduces hair loss by decreasing androgen levels.
55 citations,
November 2018 in “American journal of human genetics” Mutations in the LSS gene cause a rare type of hereditary hair loss.
44 citations,
November 1998 in “Australasian Journal of Dermatology” Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.
30 citations,
January 2014 in “Annals of Dermatology” Scalp dermatoscopy helps diagnose and monitor hair loss severity.
24 citations,
February 2006 in “Chinese Medical Journal” Cultured dermal papilla cells can regenerate hair follicles and sustain hair growth.
17 citations,
October 2003 in “Brazilian Journal of Medical and Biological Research” The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.