research Regeneration of a New Hair Follicle from the Upper Half of a Human Hair Follicle in a Nude Mouse
The upper half of a human hair follicle can grow a new hair in a mouse, but success is rare.
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research Human Hair Follicle Organ Culture: Theory, Application, and Perspectives
Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.
research Mind the Gender Gap: Does Prolactin Exert Gender and Site-Specific Effects on the Human Hair Follicle?
Prolactin may affect hair growth differently based on gender and scalp area.
research Hair Follicles and Their Role in Skin Health
Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
research Hair Follicle Generation by Injections of Adult Human Follicular Epithelial and Dermal Papilla Cells into Nude Mice
Injecting a mix of human skin and hair cells into mice can grow new hair.
research Induced Pluripotent Stem Cells from Human Hair Follicle Keratinocytes as a Potential Source for In Vitro Hair Follicle Cloning
Human hair follicle cells can be turned into stem cells that may help clone hair for treating hair loss or burns.
research Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth
Growing human skin cells in a 3D environment can stimulate new hair growth.
research Mechanistic Synergy of Hair Growth Promotion by the Avicennia Marina Extract and Its Active Constituent Avicequinone C in Dermal Papilla Cells Isolated From Androgenic Alopecia Patients
Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.
research Differential Expression of Stem Cell Markers in Human Follicular Bulge and Interfollicular Epidermal Compartments
Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.
research Tectoridin Stimulates the Activity of Human Dermal Papilla Cells and Promotes Hair Shaft Elongation in Mouse Vibrissae Hair Follicle Culture
Tectoridin helps human hair cells grow and makes mouse hair longer, suggesting it could treat hair loss.
research Putting the Human Hair Follicle Cycle on the Map
The research created a model to understand human hair growth cycle, which can help diagnose and treat hair growth disorders and test potential hair growth drugs.
research Use of the Skin Sandwich Technique to Probe the Role of Hair Follicles in Sonophoresis
Ultrasound increases skin permeability but blocks hair follicles.
research The Role of Melatonin in Neuroectodermal-Mesodermal Interactions: The Hair Follicle Synthesizes Melatonin and Expresses Functional Melatonin Receptors
Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.
research Topobiology of Human Pigmentation: P-Cadherin Selectively Stimulates Hair Follicle Melanogenesis
P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.
research An Efficient Method for Eccrine Gland Isolation from Human Scalp
Scientists developed a way to isolate sweat glands from the scalp during hair transplants, keeping them alive for 6 days for research and cosmetic uses.
research In Vitro Identification of a Stem Cell Population from Canine Hair Follicle Bulge Region
Researchers found stem cells in dog hair follicles using specific markers.
research Differences in Expression of Specific Biomarkers Distinguish Human Beard from Scalp Dermal Papilla Cells
Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.
research Activin A-Induced Signaling Controls Hair Follicle Neogenesis
Activin A is important for creating new hair follicles.
research Dermal Papilla Cell Number Specifies Hair Size, Shape, and Cycling, and Its Reduction Causes Follicular Decline
More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
research The Peripheral Clock Regulates Human Pigmentation
Certain genes control the color of human hair by affecting pigment production.
research Differential Expression of CXCL12 in Human and Mouse Hair: Androgens Induce CXCL12 in Human Dermal Papilla and Dermal Sheath Cup
The study examines the role of CXCL12 in androgenetic alopecia (AGA) by analyzing its expression in human and mouse hair follicles. It reveals that androgens increase CXCL12 expression in human dermal papilla cells (DPCs) and dermal sheath cup cells (DSCs), leading to hair miniaturization. CXCL12 is co-expressed with androgen receptors (AR) in these cells, and its increased levels are linked to hair growth inhibition. The study suggests that targeting CXCL12 with antibodies could be a promising treatment for AGA, as demonstrated by increased hair growth in testosterone-induced AGA models using human hair organ culture.
research Azasteroids as Inhibitors of Testosterone 5α-Reductase in Mammalian Skin
Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
research Autologous Cell Therapy for Aged Human Skin: A Randomized, Placebo-Controlled, Phase I Study
RCS-01 therapy is safe and may improve skin structure by affecting gene expression.
research A Role of Placental Growth Factor in Hair Growth
Placental growth factor may help treat hair loss.
research Hair Today
The document concludes that understanding hair biology is key to treating hair disorders, with gene therapy showing potential as a future treatment.
research Human Skin Stem Cells and the Aging Process
Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
research Comparison of Two In Vitro Models for the Analysis of Follicular Penetration and Its Prevention by Barrier Emulsions
Pig ear skin is better than human skin for testing how well barrier creams block allergens from entering hair follicles.
research Pharmacologic Inhibition of JAK-STAT Signaling Promotes Hair Growth
Blocking JAK-STAT signaling can lead to hair growth.
research Hair Follicle-Derived Mesenchymal Stem Cells Decrease Alopecia Areata Mouse Hair Loss and Reduce Inflammation Around the Hair Follicle
Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.
research 18-β-Glycyrrhetinic Acid Promotes Hair Growth by Stimulating the Proliferation of Dermal Papilla Cells and Outer Root Sheath Cells, and Extends the Anagen Phase by Inhibiting 5α-Reductase
Licorice extract helps hair growth and may treat hair loss.