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Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.

PRC1 influences skin stem cell development by both turning genes on and off, affecting hair growth and skin cell types.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Activating Nrf2 helps wounds heal faster by increasing hair follicle stem cells.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

The LncRNA AC010789.1 slows down hair loss by promoting hair follicle growth and interacting with miR-21 and the Wnt/β-catenin pathway.

PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

New hair follicles could be created to treat hair loss.

Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.

Dermal-epidermal interactions are crucial for hair growth and maintenance.

N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.

Targeting TGFβ can improve skin immunity in older people.

Crescina® lotion helps reduce hair loss and increase hair growth in males with androgenetic alopecia.

Increased PPARGC1α relates to hair thinning in common baldness.

Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Scientists are using clumps of special stem cells to improve organ repair.

Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.

Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Green tea compound EGCG helps mink hair follicles grow by affecting certain cell growth pathways.

Aging reduces the ability of human hair follicle cells to form new cell colonies.

Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.

Sirolimus and propranolol may reduce abnormal cell growth and improve lymphatic malformations in children.