18 citations
,
June 2010 in “Cell Stress and Chaperones” This study reported that heat treatment significantly increased the incidence of alopecia areata in C3H/HeJ mice, suggesting a role for induced HSPA1A/B expression in disease development.
3 citations
,
September 2013 in “Journal of the American Academy of Dermatology” This report details two patients with Hutchinson-Gilford Progeria syndrome who exhibited generalized shiny skin in infancy and had a novel mutation in the LMNA gene.
This study suggests that individuals with severe sickle cell disease, indicated by higher hemoglobin S and ferritin levels, may have lower cortisol levels as shown by reduced hair cortisol content.
24 citations
,
June 2012 in “BMC Research Notes” This study outlines the Human Gene Correlation Analysis tool, which classifies human genes by coexpression levels and identifies overrepresented annotation terms in correlated gene groups, with no new clinical results reported.
February 2023 in “JEADV Clinical Practice” This case report describes a girl with uncombable hair syndrome who showed significant improvement in hair combability and growth rate after two cycles of oral biotin supplementation.
9 citations
,
July 2017 in “Case Reports in Dermatology” This case study describes a 19-year-old female with hidradenitis suppurativa whose symptoms and metabolic abnormalities improved significantly over 3 years on a combined regimen, though some skin lesions persisted.
This study evaluated a hibiscus-based herbal shampoo formulation and found it to have effective cleansing and conditioning properties, mild antimicrobial benefits, and good physical stability, positioning it as a natural alternative to synthetic shampoos.
18 citations
,
June 2016 in “British Journal of Dermatology” This study found that bacterial biofilms were present in only two out of ten acute hidradenitis suppurativa lesions examined, suggesting a limited primary role for biofilms in early-stage lesions.
April 2017 in “Plastic & Reconstructive Surgery Global Open” This study suggests that while hyaluronan production by Has2 is not necessary for reepithelization, it plays a crucial role in collagen matrix reorganization during wound healing.
25 citations
,
December 2018 in “Human Molecular Genetics” This study found that the PSEN1-P242LfsX11 mutation in hidradenitis suppurativa influences cytokine and chemokine expression in macrophages, potentially affecting inflammatory responses.
17 citations
,
March 2023 in “Journal of Clinical Medicine” This study found that using PRP injections in skin flap reconstructions and combining acellular dermal matrix with split-thickness skin grafts improved healing and reduced complications in the surgical treatment of hidradenitis suppurativa.
21 citations
,
March 2015 in “Neurological Sciences” This study reports that a novel frameshift mutation in the HTRA1 gene in a CARASIL pedigree led to reduced HTRA1 protein and increased TGF-β1 expression, potentially causing severe CARASIL and peripheral small arterial disease.
296 citations
,
October 2018 in “General and Comparative Endocrinology” This review discusses the use of hair cortisol concentration as a marker for chronic stress and long-term cortisol secretion in animals, highlighting its benefits and the need for standardized sampling protocols.
2 citations
,
September 2024 in “Journal of the American Academy of Dermatology” Higher monocyte counts may predict poor response to adalimumab in hidradenitis suppurativa patients.
2 citations
,
October 2023 in “Frontiers in Public Health” This study found that in Hidradenitis Suppurativa patients, the psychosocial subscale of Skindex-17 is most relevant for assessing quality of life across different severity levels, with irritation and pain becoming more pertinent as severity progresses.
January 2025 in “Journal of Clinical Medicine” This study found that among Portuguese women with hirsutism, polycystic ovary syndrome was the most prevalent cause, associated with distinct hormonal features and higher BMI compared to controls.
5 citations
,
January 2014 in “Postepy Dermatologii I Alergologii” Among women with hirsutism studied, this research found a high prevalence of acne, particularly associated with polycystic ovarian syndrome and endocrine changes.
July 2024 in “Journal of Investigative Dermatology” Human hair follicles have their own thyroid hormone system.
1 citations
,
May 2022 in “International Journal of Pharmaceutical Sciences and Drug Research” This study reported that Hibiscus syriacus L. extracts, especially the ethanolic version, significantly reduced blood glucose and improved lipid profiles in diabetic rats, suggesting potential anti-diabetic benefits.
6 citations
,
April 2009 in “Obstetrician & gynaecologist/The obstetrician & gynaecologist” This article reviews the assessment, causes, and management approaches for hirsutism in women, emphasizing ethical considerations concerning unapproved drug use and contraceptive responsibility but reports no new clinical findings.
13 citations
,
July 2009 in “Pediatrics in Review” This review discusses the diagnosis and treatment of 21-hydroxylase deficiency in congenital adrenal hyperplasia and emphasizes the need for earlier detection and proper management; it reports no clinical results.
May 2016 in “Hair transplant forum international” This announcement reports the formation of the Hellenic Academy of Hair Restoration Surgery as a nonprofit national society in Greece; no clinical results are provided.
June 2013 in “Lithuanian University of Health Sciences” This study found no significant relationship between hormone levels and sexual function in young women with hirsutism compared to a control group.
99 citations
,
April 2005 in “Journal of Dermatological Treatment” This preliminary study suggests that finasteride may be an effective treatment option for patients with hidradenitis suppurativa, as six out of seven participants showed significant improvement.
May 2021 in “Journal of the Endocrine Society” This report presents a rare case of suspected 3β HSD deficiency in an adult female with symptoms like male pattern hair loss and low testosterone, suggesting a non-classical presentation.
November 2013 in “Hair transplant forum international” This article discusses categorization changes for Hair Transplant Surgeon members at the British Association of Hair Restoration Surgery and reports no clinical outcomes.
7 citations
,
December 2014 in “Australasian journal of dermatology” In this study, insulin resistance was observed at similar rates in non-obese women with idiopathic hirsutism, those with PCOS, and healthy controls.
1 citations
,
July 2004 in “The Journal of Dermatology” This case report describes a female patient with systemic lupus erythematosus who developed generalized hair-follicle hamartoma, marking the fourth documented association between the two conditions.
February 2020 in “Open Access Macedonian Journal of Medical Sciences” In this case report, treatment with corticosteroids improved both clinical symptoms and hormonal imbalances in a 27-year-old woman diagnosed with non-classic congenital adrenal hyperplasia.
7 citations
,
May 2014 in “Iranian Red Crescent medical journal” This case study describes a 17-year-old female with severe hirsutism diagnosed with PCOS, NC-CAH, and HAIR-AN syndrome who was successfully treated based on her specific underlying conditions.