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This study constructed a consensus single-cell atlas of hidradenitis suppurativa tunnels, identifying distinct microenvironmental endotypes with different inflammatory and fibrotic profiles, suggesting that TNF blockade may not be sufficient for addressing all lesions.

This study found that laser hair removal effectively reduces disease severity in hidradenitis suppurativa with minimal side effects, likely due to the destruction of hair follicle units.

This clinical study explores the causes, progression, and treatment of hirsutism in females, noting its association with tumors in endocrine glands, but does not report new clinical results.

This paper reviews causes of hirsutism in women and emphasizes the importance of identifying underlying conditions for risk assessment, though it reports no new clinical findings.

This article discusses the functions of the enzyme 17beta-HSD10, including its role in steroid metabolism and potential links to Alzheimer's disease, but reports no new experimental findings.

This study found that individuals with a recent history of suicide attempts exhibited altered DHEA hair levels, suggesting possible dysregulation of the HPA axis as a biopsychosocial feature, and recommends further investigation into hair hormones as potential markers of suicidal crisis and vulnerability.

This study observed substantial improvements in scalp-hair coverage, symptom burden, and psychosocial functioning in 100 patients with alopecia areata treated with individualized homeopathic medicines, noting statistically significant reductions in SALT scores and improvements in AA-IGA categories over 18 months.

This article suggests that alopecia areata may be an early skin manifestation of hereditary hemochromatosis in individuals predisposed to autoimmunity, recommending iron status evaluation during AA diagnosis; it reports no new clinical results.

This section presents 70 multiple choice questions designed for haematology specialist trainees, covering complex clinical cases and their likely diagnoses, adverse events, and management advice.

This article reviews uncombable hair syndrome, highlighting its symptoms, potential diagnosis methods, and the suggestion for biotin supplements, but it reports no new empirical results.

Antiandrogen therapy may be beneficial for women with hidradenitis suppurativa.

A Saudi girl was diagnosed with Loose Anagen Hair Syndrome, a rare condition causing easy hair loss without scarring.

This article reviews hirsutism in adolescent females, discussing its hormonal basis, potential underlying conditions, and the availability of effective therapies, without reporting new research findings.

This study found that idiopathic hirsutism was the most common cause of hirsutism among patients, and insulin resistance was significant in those with Hyperandrogenic Insulin Resistant Acanthosis Nigricans Syndrome.

This case series reported that three pediatric patients with hidradenitis suppurativa showed decreased frequency and severity of disease flares after treatment with oral finasteride, with no significant adverse effects.

This study evaluated interleukin-26's antimicrobial activity in Hidradenitis Suppurativa and explored its potential role in chronic skin inflammation.

This study found that inhibiting the interaction between HOTAIR and EZH2 can block pro-fibrotic gene expression in fibroblasts and interfere with tissue remodeling in systemic sclerosis patient skin.

This study conducted physical examinations on fifty women with hirsutism, focusing on virilization signs, but reports no new clinical findings.

This study reports that oral spironolactone may be a useful and low-cost first-line treatment for hidradenitis suppurativa in women, with relatively few side effects.

This study mapped a spontaneous mouse hair mutation, "hague," to keratin genes on chromosome 15 but found no gene mutations in hague mice.

This review synthesizes knowledge on HTRA1-associated disorders, highlighting how mutations in the HTRA1 gene are linked to cerebral small vessel disease and systemic conditions, and discusses emerging diagnostic and therapeutic strategies aimed at precision medicine.

This overview describes various disorders, including haphephobia, alopecia areata, and urinary incontinence, summarizing potential treatments and management strategies specific to each condition.

In this study, researchers found that in Germany, orphan drugs with a phase III study and no comparable treatments available tend to receive higher HTA scores. There was no significant correlation between HTA scores and orphan drug prices or discount rates.

This article offers a viewpoint on hidradenitis suppurativa pathogenesis, suggesting that impaired Notch signalling from γ-secretase mutations may drive inflammation and link the condition to other Th17-driven diseases.

This review examines the causes, assessment, and treatment options for hirsutism but presents no new clinical findings, highlighting the need for further research on managing this condition.

This study found that notch1 signaling is severely impaired in hidradenitis suppurativa patients with or without NCSTN or other gamma-secretase gene mutations, highlighting a canonical defect at the lesional tissue level.

This overview describes the Dermatologic Surgery journal's extensive focus on peer-reviewed dermatologic surgery content, but it reports no new research findings.

This study found that hirsute women had a significantly higher incidence of psychological issues compared to controls, unrelated to the severity of their hirsutism or androgen levels.

This review discusses the pathophysiology, molecular genetics, and management of non-classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency, with no new clinical findings reported.