Item-Specific Patterns of the Skindex-17 in Individuals With Different Levels of Hidradenitis Suppurativa Severity: A Network Analysis Study

This study examined the relationship between Hidradenitis Suppurativa (HS) severity and Skindex-17 responses in 547 adults, using network analysis to identify patterns in item associations. It found that certain item pairs were consistently linked across all severity levels, suggesting these items are unaffected by severity changes. Items related to social life and emotional well-being were central to understanding quality of life, while physical symptoms gained importance in moderate to severe cases. The study suggests that addressing psychosocial symptoms could improve clinical outcomes, despite limitations like the cross-sectional data and self-report biases.