Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, BLIMP1 was found to function in terminally differentiated epidermal cells to maintain homeostasis, rather than defining a sebocyte progenitor population.

This review explores the potential (neuro-)endocrine influences on hair follicle epithelial stem cell biology and emphasizes the need for more systematic research, but it provides no new empirical results.

This review discusses the role of the hairless protein (HR) in alopecia and cancer, noting its potential importance in cancer cell growth and survival, and reports no new experimental results.

This review discusses the embryology, structure, and function of sebaceous glands and their involvement in skin disorders but reports no novel findings.

In this study, structural and functional brain abnormalities specific to visuospatial and somatosensory processing networks were observed in patients with anorexia nervosa, highlighting a critical role for the precuneus.

This study of Liaoning cashmere goats identified nine keratin proteins as markers of the secondary hair follicle cycle, providing insights that may enhance cashmere quality and production.

This study identified key genes and pathways involved in the seasonal hair cycle regulation of yak, uncovering molecular mechanisms that may aid in understanding their adaptation to alpine environments.

This study suggests that seasonal rhythm genes in cashmere goat skin are differentially expressed with changing daylight, potentially affecting hormone transformation and light sensitivity.

This study observed distinct sex differences in hair growth cycles and regeneration in C3H/He mice, noting that females regenerated hair faster after adhesive material application, whereas males were more reliant on macrophage activity for this process.

In a mouse model, this study found that exposure to PM2.5 leads to significant postpartum hair loss, apparent via morphological changes and elevated markers of inflammation, apoptosis, and fibrosis, potentially exacerbated by changes in hormone receptors and stem cell populations.

In this study, researchers developed a novel genetic tool using Wif1-CreER knock-in mice for precise labeling and manipulation of dermal papilla cells, which could enhance understanding of hair biology and aid in developing targeted therapies for hair-related disorders.

This study found that cell-free fat extract (CEFFE) enhanced hair growth in mice with androgenetic alopecia by increasing hair follicle density and promoting proliferation while regulating the DHT/AR pathway.

This study observed that in a mouse model of androgenetic alopecia, treatments with LTF, 5% minoxidil, and LTF-DPC-EXO significantly promoted hair regeneration compared to the model group, potentially through modulation of the PI3K/AKT signaling pathway.

This paper introduces a framework attributing Post-SSRI, Post-Finasteride, Post-Retinoid, and an unnamed sexual dysfunction syndrome to downregulated estrogen receptor activity, potentially guiding future treatments in sexual medicine.

This study found that in mice, chronic stress elevates corticosterone levels, which suppresses hair growth by keeping hair follicles in a prolonged resting phase.

This review discusses the potential roles of androgens and antiandrogens in COVID-19 outcomes, noting unresolved questions about their effectiveness and safety for treatment.

This study found that cell strains overexpressing the androgen receptor proliferated better in low or no DHT conditions and translocated AR more efficiently than control strains.

This review explores the role of the TMPRSS2 gene in facilitating SARS-CoV-2 infection and its potential as a therapeutic target in COVID-19 and other respiratory infections, highlighting challenges in developing selective inhibitors.

The researchers reported that DHT may reduce the inflammatory responses induced by C. acnes in androgen-sensitive human sebocyte cells, suggesting a potential link between androgens and infection in sebaceous disorders.

This study found that areola formation in mice requires a combination of pregnancy hormones and mechanical strain, with individual stimuli causing only modest changes in epidermal proliferation and connective tissue remodeling.

This review examines the neuroendocrine mechanisms underlying seasonal changes in mammals and highlights areas needing further research, reporting no new experimental results.

This article discusses the role of human scalp hair follicles in neurohormone production and their model potential for studying neuroendocrine signaling, reporting no experimental results.

This study found that human scalp hair follicles can respond to corticotropin releasing hormone stimulation similarly to the classical HPA axis, including up-regulating cortisol production and activating neuroendocrine feedback loops.

This hypothesis paper suggests that PCOS may result from genetically determined ovarian hypersecretion of androgens, influencing hormone regulation and insulin resistance, with obesity further affecting its severity; no new clinical results are reported.

This article discusses the potential role of a local skin POMC system in the murine hair cycle and cutaneous stress responses, with no new results presented.

This review discusses potential mechanisms contributing to higher COVID-19 mortality among men, particularly the roles of smoking, genetic factors, and reproductive hormones, without presenting new clinical findings.

This study found that testosterone and 5α-dihydrotestosterone induced apoptosis in dermal papilla cells from nonbalding scalp regions, suggesting a high androgen stimulus can trigger cell death related to androgenetic alopecia.

This article summarizes findings on the role of androgens and estrogens in male reproductive tissues across species, highlighting the roles of hormone metabolism, receptor distribution, and stress-induced changes.

This article reviews sebaceous immunobiology and highlights the complex role of sebaceous glands and sebocytes in skin barrier function and inflammation, particularly in acne pathogenesis, but reports no new results.

This review explores the potential impact of hormonal changes during aging on benign prostate hyperplasia-related urinary symptoms and metabolic syndrome, highlighting the hypothesis of a male PCOS-equivalent but reports no new clinical results.