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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Skin problems are very common in people with end-stage kidney disease.