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Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

Evaluate postmenopausal women with high androgen levels using medical history, physical exams, lab tests, and imaging to manage health risks.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.

Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

Using psychological treatments can help manage skin conditions along with regular medical care.

Prolactin may be important for skin growth and immune function.

Some alternative treatments for hair loss might work, but more research is needed.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The study concluded that both anti-Mullerian hormone and LH/FSH ratio are higher in women with PCOS and combining these markers with BMI could improve diagnosis accuracy.

Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.

Hair follicle stem cells and skin cells show promise for hair and skin therapies but need more research for clinical use.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.