28 citations
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January 2012 in “Biological & pharmaceutical bulletin” This study found that the protein hairless acts as both a corepressor and coactivator of the vitamin D receptor, influencing gene transcription in a ligand-selective manner.
January 2025 in “Indian Journal of Unani Medicine” This case study observed that hijāmah bil shart (wet cupping) led to significant improvements in hair texture, reduced shedding, and overall scalp health in a 34-year-old male with androgenetic alopecia, with no adverse effects.
27 citations
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October 2018 in “Saudi Journal of Biological Sciences” This study found that curcumin administration improved cognitive and anxiety-related behaviors and neurochemical levels in HgCl2 exposed mice pups, suggesting protective effects against heavy metal-induced neurotoxicity.
1 citations
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January 2017 in “Springer eBooks” The document explains how hair loss patterns in men and women, known as Androgenetic alopecia, are classified using the Hamilton-Norwood system for men and the Ludwig grade system for women.
37 citations
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October 2006 in “Archives of Biochemistry and Biophysics” This study describes a patient with hereditary vitamin D resistant rickets (HVDRR) who, despite having a truncated vitamin D receptor, did not exhibit typical hair or skin abnormalities, suggesting possible compensation via interactions with other proteins.
February 2022 in “The Nurse Practitioner” This article provides an introduction to gender-affirming hormone therapy for transgender and gender-nonbinary patients, designed as a continuing education activity, but does not report new clinical results.
March 1996 in “Hair transplant forum international” This article discusses the formation and goals of the World Association of Hair Replacement Surgeons, focusing on the exchange of advanced hair restoration surgery techniques, without presenting new research findings.
2 citations
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February 2021 in “Case reports in dermatological medicine” In this case series, the topical botanical formulation GASHEE demonstrated significant improvements in hair regrowth without adverse events among patients with hair loss, including cases where previous treatments had failed.
72 citations
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October 2009 in “The FASEB journal” This study found that thyrotropin-releasing hormone (TRH) acts as a potent stimulator of hair growth in human scalp hair follicles, promoting elongation and prolonging the anagen phase.
August 2020 in “Pakistan Journal of Zoology” This study identified a novel genetic mutation, c.429delC in the hairless gene, associated with atrichia with papular lesions in two Pakistani families.
April 2026 in “International Journal of Dermatology”
8 citations
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March 2023 in “Journal of Clinical Epidemiology” This updated guidance from the GRADE working group addresses issues with assessing inconsistency in treatment effect estimates and evaluating the credibility of effect modifiers in systematic reviews.
August 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This article discusses how activating the hexosamine pathway may enhance skin homeostasis by increasing hyaluronic acid secretion and supporting hair follicle stem cell self-renewal, but reports no new results.
1 citations
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July 2021 in “Acta dermatovenerologica Croatica” This case report describes regression of hidradenitis suppurativa lesions in two patients after 16 weeks of adalimumab treatment.
September 2009 in “International Society of Hair Restoration Surgery” This article updates on the American Board of Hair Restoration Surgery's growth over 11 years, noting 134 Diplomates from 15 countries and 10 new Diplomates from five countries after the January 2009 exam; it reports no scientific findings.
42 citations
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July 2015 in “Journal of The American Academy of Dermatology” This review discusses diagnostic and treatment considerations for women with cutaneous hyperandrogenism, noting therapeutic options are more effective for hirsutism and acne than for androgenetic alopecia, but reports no new clinical results.
158 citations
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January 2003 in “Journal of Forensic Sciences” This study demonstrates that a single exposure to GHB during a sexual assault can be detected by analyzing hair segments collected about one month after the incident.
March 2007 in “Journal of hypertension” Minoxidil effectively lowers blood pressure in patients with resistant hypertension.
4 citations
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January 1997 in “EXPERIMENTAL ANIMALS” This study suggests that increased activity of the histamine synthesizing enzyme histidine decarboxylase may play a role in initiating the anagen phase of hair regrowth in mice.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that Myelin Protein Zero-like 3 plays a crucial role in hair follicle cycling by regulating anagen and catagen phases, mediated through mitochondrial signaling mechanisms in both human and murine hair follicles.
This study found that administering gingerol improved survival and reduced organ damage in mouse models of chronic graft-versus-host disease by modulating T cell differentiation and inflammatory cytokines, suggesting a novel therapeutic approach for steroid-refractory cases.
October 2023 in “Case Reports” This case report identified a new isotype of male androgenetic alopecia (inverse-MAGA) in a man successfully treated with finasteride and minoxidil, suggesting the need for future studies to evaluate this variant widely.
29 citations
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April 2019 in “Lasers in Medical Science” This study found that combining fractional erbium-glass laser therapy with topical minoxidil significantly improved hair density and diameter in men with androgenetic alopecia compared to using minoxidil alone over a 24-week period, with no serious adverse events reported.
June 2021 in “The American Journal of the Medical Sciences” This study found that patients with androgenetic alopecia had higher serum homocysteine levels, linked to the mutant MTHFR genotype, and an increased risk of coronary heart disease.
4 citations
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May 2020 in “Medicine in Drug Discovery” This study found that arylsulfatase enzymes in hair follicles can convert the active form of minoxidil back to its inactive form, potentially affecting its effectiveness in treating androgenetic alopecia.
September 2025 in “The Professional Medical Journal” In this study, 5mg oral minoxidil given daily for 24 weeks significantly increased hair thickness and scalp appearance among 27 male patients with androgenetic alopecia, although some experienced side effects like hypertrichosis and mild headaches.
2 citations
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April 2008 in “PubMed” This study identified the c.1204G to A (p.E402K) mutation in the hHB6 gene as a cause of monilethrix in a Chinese family, highlighting the gene's role in the condition.
67 citations
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August 2007 in “American Journal of Pathology” This study found that overexpression of the mineralocorticoid receptor in a mouse model led to premature epidermal barrier development, keratinocyte apoptosis, and postnatal alopecia, indicating new roles for MR signaling in skin physiology.
February 2024 in “International Journal of Biological Macromolecules” In this study, researchers developed a microfluidic-assisted technology to create dual-layer microspheres containing mesenchymal and epidermal cells, which efficiently induced hair follicle regeneration in mice, suggesting potential improvements for hair regeneration treatments in conditions like androgenetic alopecia.
April 2022 in “Microbiology and Immunology” This study suggests that a specific short sequence repeat in Malassezia restricta may be linked to increased colonization and the development or exacerbation of androgenetic alopecia.