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    Glossary HLA-DR

    protein on immune cells presenting antigens to trigger responses

    HLA-DR is a part of the human immune system, specifically a protein found on the surface of certain cells that helps the body distinguish between its own cells and foreign invaders. It plays a crucial role in the immune response by presenting pieces of proteins (antigens) to immune cells, which can then trigger an immune reaction. This protein is also involved in autoimmune conditions, where the immune system mistakenly attacks the body's own tissues.

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    1. Epigallocatechin-3 Gallate Inhibits STAT-1/JAK2/IRF-1/HLA-DR/HLA-B and Reduces CD8 MKG2D Lymphocytes of Alopecia Areata Patients 2018 · 15 citations
    2. Human Adipose-Derived Mesenchymal Stromal Cells Exhibit High HLA-DR Levels and Altered Cellular Characteristics under a Xeno-free and Serum-free Condition Stem Cell Reviews and Reports · 2021 · 12 citations
    3. Changes in Populations of HLA- DR+CD3+ Cells and CD57–CD16+ Cells in Alopecia areata after Corticosteroid Therapy Dermatology · 1994 · 5 citations
    4. [Significance of HLA-DR+ T cells and natural killer (NK) cells in the peripheral blood lymphocytes of alopecia areata (AA)]. PubMed · 1990 · 2 citations
    5. Human Adipose-derived Mesenchymal Stromal Cells Exhibit High HLA-DR Levels and Altered Cellular Characteristics under a Xeno-free and Serum-free Condition Research Square (Research Square) · 2021
    6. Immunogenetic and metabolic risk factors in male androgenetic alopecia: the role of HLA-DRB1 alleles and vitamin D3 deficiency 2025
    7. Genetic association of <i>HLA‐DQB1</i> and <i>HLA‐DRB1</i> polymorphisms with alopecia areata in the Italian population British Journal of Dermatology · 2011 · 35 citations
    8. Identification of drug-specific public TCR driving severe cutaneous adverse reactions Nature communications · 2019 · 88 citations
    9. Alopecia Areata is associated with MICA and an extended HLA haplotype Journal of the American Academy of Dermatology · 2004 · 1 citations
    10. THE PATHOGENESIS OF ALOPECIA AREATA Dermatologic Clinics · 1996 · 89 citations
    11. The spectrum of hair loss in patients with mycosis fungoides and Sézary syndrome Journal of The American Academy of Dermatology · 2010 · 39 citations
    12. Human Leukocyte Antigen Class II Alleles Are Associated with Risk of Alopecia Areata Journal of Investigative Dermatology · 2007 · 36 citations
    13. Alopecia areata patients show deficiency of FOXP3+CD39+ T regulatory cells and clonotypic restriction of Treg TCRβ-chain, which highlights the immunopathological aspect of the disease PloS one · 2019 · 30 citations
    14. Pemphigus vulgaris in only one of two monozygotic twins Journal of The American Academy of Dermatology · 1985 · 20 citations
    15. Exomic Sequencing of Immune-Related Genes Reveals Novel Candidate Variants Associated with Alopecia Universalis PLoS ONE · 2013 · 18 citations
    16. RETRACTED: Causal role of immune cells in alopecia areata: A two‐sample Mendelian randomization study Skin Research and Technology · 2024 · 14 citations
    17. Lepromatous Leprosy in a Renal Transplant Recipient Clinical Infectious Diseases · 1998 · 12 citations
    18. [Selective changes in lymphocytic differentiation antigens in the peripheral blood of patients with alopecia areata treated with oral zinc]. PubMed · 1990 · 11 citations
    19. Exacerbation of alopecia areata during pegylated interferon alpha-2b and ribavirin therapy, possibly due to the collapse of hair follicle immune privilege European Journal of Dermatology · 2014 · 10 citations
    20. Vogt-Koyanagi-Harada Disease: A Narrative Review Cureus · 2024 · 9 citations
    21. Clinical and Genetic Aspects of Alopecia Areata: A Cutting Edge Review Genes · 2023 · 1 citations
    22. Alterations in epidermal stem cells within the pilosebaceous unit in atrophic acne scars Australasian journal of dermatology · 2024
    23. Epidermolysis Bullosa Acquisita Occuring In A Patient With Systemic Lupus Erythematosus Saintika Medika · 2019
    24. Case report: a study of the clinical characteristics and genetic variants of post-finasteride syndrome patients Translational Andrology and Urology · 2022
    25. Hyperthyroidism Pediatrics in Review · 2006
    26. Autoimmunity: Alopecia Areata Journal of Investigative Dermatology Symposium Proceedings · 2004 · 143 citations
    27. Major Histocompatibility Complex Class I Chain-Related Gene A Polymorphisms and Extended Haplotypes Are Associated with Familial Alopecia Areata Journal of Investigative Dermatology · 2005 · 44 citations
    28. Association of psoriasis and psoriatic arthritis with human leukocyte antigen and killer cell immunoglobulin–like receptor gene frequency: A multiethnic population study Journal of The American Academy of Dermatology · 2009
    29. Study of Human Leukocyte Antigen ( HLA ) in 13 cases of familial frontal fibrosing alopecia: CYP 21A2 gene p.V281L mutation from congenital adrenal hyperplasia linked to HLA class I haplotype HLA ‐ A*33:01 ; B*14:02; C*08:02 as a genetic marker Australasian Journal of Dermatology · 2019 · 7 citations
    30. ONKOLOGIA OKULISTYCZNA WCZORAJ I DZIŚ Wiadomości Lekarskie · 2024