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Topoisomerase inhibitors can cause hair loss, skin rash, hand-foot syndrome, and nail changes.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

The document is a detailed medical reference on skin and genetic disorders.

Nonpalmoplantar skin cells can be made to express keratin 9 by interacting with palmoplantar fibroblasts.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.

The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.

Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.

Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.

Somatostatin may help protect hair follicles from immune attacks.

Hair follicles prevent NK cell attacks to avoid hair loss.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Tofacitinib temporarily regrew hair in a man with alopecia, but its effects didn't last.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Early detection and stopping the drug are key to managing DRESS, and careful monitoring is important due to possible severe reactions.

The document concludes that reactivation of herpesviruses, especially HHV-6, is linked to severe symptoms and complications in drug-induced hypersensitivity syndrome.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Early treatment of mixed connective tissue disease is crucial to prevent severe autoimmune conditions.

Amniotic allograft may be more effective than platelet-rich plasma for midface aging treatment.

Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.

Stress hormones and autoimmune reactions can cause hair loss.

Genetic discoveries are leading to new treatments for alopecia areata.

Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

The document concludes that Cutaneous Lupus Erythematosus has different forms, is influenced by genetic and environmental factors, and can be treated with various medications, but more targeted therapies are needed.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Some women with excess hair growth have a hormone condition that can't be diagnosed by blood or urine tests alone.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

Vitamin A affects hair loss and immune response in alopecia areata.

The document explains various skin conditions and their treatments.