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Belimumab effectively reduces disease activity in lupus patients, regardless of initial serologic status.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

The Polish Dermatological Society recommends personalized treatment for cutaneous lupus, including lifestyle changes, medications, and monitoring, with specific drugs for severe cases.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Different connective tissue disorders have unique symptoms and treatments, with varying outcomes and often require ongoing care from a specialist.

Researchers identified promising inhibitors for the BRD4 protein, including finasteride and amentoflavone.

Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.

Biotin supplements increased biotin levels but did not significantly prevent hair loss in rats on valproic acid.

Valproic acid may cause hair loss by reducing biotinidase enzyme activity in rats.

Improving mitochondrial health may better treat atherosclerosis than antioxidants.

GDNF helps grow hair and heal skin wounds by acting on hair stem cells.

Targeting NCoR1 can help treat heart enlargement and dysfunction.

Autophagy changes the protein makeup of hair.

Relatives of lupus patients show signs of immune system activity but not full-blown lupus.

Mutations in mitochondrial DNA might significantly contribute to the development of Polycystic Ovarian Syndrome.

Certain short peptides can increase root hair growth in tobacco plants.

PRP therapy is effective for hair regrowth and improving hair quality with minimal side effects.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.

Vitamin D is important for bones, hair, blood pressure, and breast development.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

Trichohyalin is a protein in hair follicles that helps form hair filaments.

Metabolic signals and cell shape influence how cells develop and change.

Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.

Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.

IL-3 worsens lupus nephritis and blocking it improves kidney health.

Metabolism plays a key role in determining stem cell fate.

Catalytic antibodies are early indicators and active participants in the development of systemic lupus erythematosus.