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Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

The current understanding of frontal fibrosing alopecia involves immune, genetic, hormonal factors, and possibly environmental triggers, but more research is needed for effective treatments.

Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.

HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.

KLF4 is important for maintaining skin stem cells and helps heal wounds.

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

The tropical legume Sesbania rostrata can form nodules in waterlogged conditions using a different method that involves plant hormones and specific genes.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Nellore cattle have genetic variations linked to their adaptation to tropical environments.

Different human hair follicle stem cells grow at different rates and respond differently to a baldness-related compound.

Hes1 protein is important for hair growth and regeneration, and could be a potential treatment for hair loss.

MED1 affects skin wound healing differently in young and old mice.

Poplar seed hairs grow from the placenta at the ovary base, with endoreduplication playing a key role in their development, and share similar cellulose synthesis processes with cotton fibers.

Sodium Valproate nanospanlastics could be a safe and effective treatment for Androgenic Alopecia, with fewer side effects than minoxidil.

Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.

Small molecule IM boosts hair growth by changing stem cell metabolism.

Eating less can slow aging and help keep stem cells healthy by cleaning out damaged cell parts.

The gene Msx2 is crucial for hair follicle regeneration during wound healing.

Non-immune factors play a significant role in alopecia areata.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.

The hair follicle bulge is an important area for adult stem cells involved in hair growth and repair, with potential for medical use needing more research.

A gene called Gk5 controls lipid production in the skin and affects hair growth.

Vitamin D boosts a specific protein in skin cells linked to hair follicles.

Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.

The HOXC13 gene affects different hair proteins in cashmere goats in varied ways and is controlled by a feedback loop and other factors.

The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.

The G60S Connexin43 mutation causes hair growth issues and poor hair quality in mice, similar to human ODDD patients.