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The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.

Targeting NCoR1 can help treat heart enlargement and dysfunction.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Sodium valproate is effective in treating epilepsy, especially in patients who don't respond to other medications.

A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.

CDP is crucial for lung and hair follicle cell development.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.

Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

Vitamin D receptor helps control hair growth genes in skin cells.

Valproate is a mood stabilizer for bipolar disorder but has side effects and risks, especially during pregnancy.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

Human hair protein modifications could potentially indicate heart disease risk.

Nuclear shape and chromatin changes affect gene expression in skin cell differentiation.

Goat skin changes with the seasons due to genes affected by daylight and hormones.

Eating high-glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.

Clim proteins are essential for maintaining healthy corneas and hair follicles.

The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.

Sox6 is important in heart and kidney health, affecting diseases like diabetes, heart disease, and high blood pressure.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Men with a family history of hair loss on their mother's side are more likely to have female pattern hair loss.

The Notch signaling pathway is important for hair follicle development and could help create treatments for hair disorders.

AcSDKP may help prevent skin and hair aging and promote their growth.

The study suggests that higher levels of SIRT1 and SIRT2 may improve overall cell health and aging processes.

Nrf2 helps protect skin from damage but too much can cause skin problems.

Some treatments can improve skin's defense against damage, but overuse may cause other skin problems.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.