6 citations
,
November 1980 in “Clinical Endocrinology” This study measured plasma testosterone glucosiduronate levels and found no overlap in those with hyperandrogenism compared to normal females, despite normal testosterone and dihydrotestosterone levels in half of the affected patients.
This study found that human growth hormone encapsulated in nano-liposome increased the number of hairs and stimulated hair cycling in mice, suggesting potential benefits for addressing hair loss.
April 2018 in “Journal of Investigative Dermatology” This study found that the absence of Hes1 in hair follicles delays secondary hair germ activation and shortens the anagen phase, impacting HFSC self-renewal and long-term hair regeneration.
2 citations
,
January 2013 in “Türkiye klinikleri tıp bilimleri dergisi” This study found that a modified Ferriman-Gallwey score of 11 may be appropriate for diagnosing hirsutism in Turkish women, but should be adjusted based on individual factors like age, skin type, and family history.
4 citations
,
June 2017 in “Anais Brasileiros De Dermatologia” This study demonstrates that miniaturized hair follicles in female pattern hair loss overexpress nuclear aryl hydrocarbon receptors, suggesting a potential role for environmental pollutants in this condition.
June 2025 in “Medical alphabet” This study found that the manual hair transplantation method HFE may offer better precision and cosmetically satisfying results with minimal tissue trauma for treating androgenetic alopecia in men.
This study found that polycystic ovary syndrome was the most common cause of hirsutism among premenopausal Algerian women, affecting nearly 60% of participants.
37 citations
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June 2004 in “Human molecular genetics online/Human molecular genetics” This study suggests that the HCR risk allele within the PSORS1 locus may contribute to psoriasis susceptibility by altering gene expression related to skin structure and differentiation, although these changes alone might not result in clinical symptoms.
7 citations
,
July 2019 in “International Journal of Molecular Sciences” This study found that PGA-4HGF nanoparticles enhanced hair growth in mice more effectively than 4HGF alone by increasing anagen phase duration and dermal papilla cell proliferation.
1 citations
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October 2020 in “Journal of Cosmetic Dermatology” In this study, premature hair graying in Egyptians was significantly linked to family history, stress, sedentary lifestyle, and low serum ferritin levels, but not to vitamin D deficiency.
January 2002 in “Proceedings of The Japanese Society of Animal Models for Human Diseases” In this study, researchers observed distinct morphological differences in hair follicles of mutant mouse genotypes, influenced by the expression levels of keratin2-6g, which is essential for proper hair follicle development.
8 citations
,
March 2023 in “Journal of Clinical Epidemiology” This updated guidance from the GRADE working group addresses issues with assessing inconsistency in treatment effect estimates and evaluating the credibility of effect modifiers in systematic reviews.
2 citations
,
September 2004 in “Fertility and sterility” This review discusses the cosmetic and health implications of hirsutism and highlights its potential link to serious underlying disorders, but it presents no new clinical findings.
42 citations
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July 2007 in “Journal of Biological Chemistry” This study found that most pathogenic HR mutants associated with atrichia with papular lesions had abolished corepressor activity due to defective interactions with histone deacetylases.
May 2025 in “Journal of Craniofacial Surgery Open” This case study observed that high-intensity focused ultrasound treatment significantly improved hair density and reduced hair loss in a female patient with androgenetic alopecia, with no adverse events reported.
14 citations
,
December 2021 in “International journal of molecular sciences” This article reviews current knowledge and research gaps on growth hormone in hair follicle biology, highlighting its complex role and suggesting further exploration to reveal nonclassical skin functions.
November 2024 in “Journal of Investigative Dermatology” Dermal IgA deposition without symptoms is rare in Dermatitis herpetiformis risk groups.
3 citations
,
January 2013 in “Journal of cosmetics, dermatological sciences and applications” This study found that the new HCC additive enhances the permeation of pigments and active ingredients into hair, suggesting potential use in developing functional cosmetic hair products.
In this study, researchers evaluated hirsutism in young females aged 18-24 using the modified Ferriman-Gallwey scoring system, finding that 52% showed mild to moderate-to-severe symptoms, often linked to menstrual irregularities and underlying endocrine disorders like polycystic ovary syndrome and thyroid issues.
3 citations
,
December 2019 in “Journal of Cosmetic and Laser Therapy” This study found that plasma rich in growth factors showed promising results for increasing hair number and thickness in androgenic alopecia patients, with better outcomes after multiple injections.
55 citations
,
July 1997 in “Clinical Endocrinology” This study found that administering growth hormone to adult men with GH deficiency increased their sexual hair scores, suggesting an auxiliary effect on androgen action in the skin.
October 2024 in “GE Portuguese Journal of Gastroenterology” This case report describes a 78-year-old male with adenocarcinoma and Hypertrichosis lanuginosa acquisita, highlighting the need to consider malignancy in patients with unexplained excessive hair growth.
6 citations
,
March 1996 in “Journal of Investigative Dermatology”
July 2024 in “Journal of Pediatric Endocrinology and Metabolism” This study presents two adolescent cases of ovarian hyperthecosis, a rare cause of severe hyperandrogenism, highlighting management strategies involving gonadotropin suppression and hormone replacement after excluding androgen-producing adrenal and ovarian tumors.
8 citations
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January 1991 in “Soviet physics. Doklady” This article suggests that testosterone therapy might be considered if other treatments fail, but emphasizes discussing potential risks and benefits with patients before prescribing.
January 2010 in “Chinese Journal of Dermatovenereology of Integrated Traditional and Western Medicine” This study found a novel nonsynonymous genetic variant in the hHb1 gene of a family with monilethrix, which differs from ten previously reported pathogenic mutations.
March 2024 in “The journal of sexual medicine” This case study observed that in four middle-aged men with ejaculation disorders, therapy with human chorionic gonadotropin (hCG) alone or combined with recombinant follicle-stimulating hormone (rFSH) improved sexual desire, semen volume, and various other symptoms, although some experienced elevated estradiol levels and hair loss.
1 citations
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May 2019 in “Journal of The European Academy of Dermatology and Venereology” New method, hair distribution width (HDW), improves accuracy in diagnosing androgenetic alopecia (AGA).
92 citations
,
July 2001 in “The FASEB Journal” In this study, transgenic mice overexpressing the glucocorticoid receptor in certain epithelia showed skin development abnormalities resembling ectodermal dysplasia and exhibited reduced inflammatory responses.
85 citations
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March 2008 in “Journal of Cell Science” This study created transgenic mouse models with the LMNA gene mutation common in Hutchinson-Gilford progeria syndrome, revealing skin and teeth abnormalities related to transgene expression levels.