Evaluating Effect of HCG and HCG+RFSH Therapy on Ejaculation Disorders in Middle-Aged Men: A Case Study

    Hideyuki Kobayashi, Masataka Uetani, Koichi Nakajima, Kōichi Nagao, Nazrul Islam
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    TLDR The therapies improved ejaculation disorders and sexual function in middle-aged men.
    This case study evaluated the effects of hCG and hCG+rFSH therapy on ejaculation disorders in four middle-aged men (aged 55-59). The therapies aimed to address low semen volume and decreased ejaculatory pleasure. One patient received hCG+rFSH, while three received hCG alone. Results showed increased testosterone levels and improved sexual function across all patients, with some experiencing elevated estradiol (E2) levels managed by adding anastrozole. Notable improvements included increased semen volume, enhanced libido, and better glycemic control in a diabetic patient. Side effects included hair loss in one patient. Overall, the therapies were effective in improving symptoms of ejaculation disorders.
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