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This review discusses ovarian hyperthecosis as a rare cause of androgenetic alopecia in postmenopausal women and reports no new results; the authors highlight the need to explore its relationship to alopecia further.

This study found that the phenotype of Hedgehog/Gli-driven skin tumors in mice depends on the cell of origin, tissue context, and level of oncogenic signaling.

In this study, researchers conducted additional IHC staining on equine skin sections and found that collagen type III primarily labels the extracellular matrix, while anti-PDGFR-antibody staining highlights cells with long-shaped processes mainly arranged around hair follicles.

This manuscript describes two case reports of preterm newborns with a rare homozygous mutation in the epidermal growth factor receptor, leading to severe health issues and early mortality despite supportive care.

This study reviewed evidence on eribulin's efficacy and safety for treating metastatic triple-negative breast cancer, highlighting variable survival outcomes and manageable safety profiles for both monotherapy and combination therapies.

This case report highlights a rare instance of postmenopausal virilization in a 71-year-old woman due to coexisting ovarian hilus cell hyperplasia and a Sertoli-Leydig cell tumor.

This case study reports that a 16-year-old girl with hirsutism and menstrual irregularities was diagnosed with a benign steroid cell ovarian tumor, after high testosterone levels indicated a potential androgen-secreting source.

This study found that estrogen receptor beta, not alpha, is the main mediator of estrogen action in human skin and hair follicles, suggesting a distinct role in these tissues.

This study found that the E6 gene, but not E7, was responsible for HPV8-induced expansion of keratinocyte stem cells in hair follicle junctional zones in mice.

In this study, animal model observations suggested that GLI1 expression may reduce cSCC initiation but is not involved in the tumor's aggressiveness.

In this case report, a transgender woman with refractory epilepsy began estrogen therapy for gender-affirming purposes, experiencing stable epilepsy and reduced gender dysphoria through ongoing multidisciplinary care, highlighting the importance of careful management for similar patients.

This study in Senegal reported that among women with hyperandrogenism, the primary diagnosis was polycystic ovarian syndrome, with symptoms including hirsutism, menstrual disorders, and acne.

This case series observed that ovarian hyperthecosis can manifest with hyperandrogenism and insulin resistance in postmenopausal women, even when serum testosterone levels are below diagnostic thresholds, suggesting potential gaps in current diagnostic criteria.

This review highlights the role of matriptase in epithelial differentiation and cancer, noting that unregulated matriptase expression can enhance cancer progression in animal models, but reports no new experimental data.

This review outlines the existing literature on gender-affirming hormone therapy and cancer risk among transgender populations but offers no new clinical findings, highlighting the need for more research to address cancer health disparities.

This study reviewed evidence on the role of specific genes (FKBP12, SAMAHD1, TRF2, CD155, and GATA3) in predicting how breast cancer patients might respond to adjuvant chemotherapy, aiming to monitor these markers in blood or tissue samples.

This case study found that a 1.6cm ovarian Leydig cell tumor, causing hyperandrogenism in a postmenopausal woman, evaded detection on standard imaging techniques, underscoring the difficulty of diagnosing such tumors with imaging alone.

This study found that MYH9 acts as a tumor suppressor in squamous cell carcinomas by stabilizing p53 in the nucleus, suggesting its role in cancer prevention.

This study found that overexpression of the metabolic enzyme PHGDH can promote cancer initiation and progression, highlighting its significant role in tumor cell proliferation and tumorigenesis.

This report highlights two cases where trichoblastoma in the breast was initially misdiagnosed as malignancy due to diagnostic challenges in needle core biopsies, emphasizing the importance of expert dermatopathologic review.

This study found that in a transgenic mouse model, β-HPV infection led to increased skin thickness and proliferation of specific keratinocyte stem cells, which may contribute to squamous cell carcinoma development.

This study revealed that nestin-expressing progenitor cells capable of becoming ORS keratinocytes are present during both hair follicle development and in adult hair follicles.

In this study, nestin-expressing cells in the hair follicle bulge, marked by GFP in transgenic mice, were identified as progenitors of the hair follicle outer-root sheath.

This review discusses the characteristics, diagnostic challenges, and management options for postmenopausal hyperandrogenism but reports no new clinical results; it highlights the importance of distinguishing potential androgen-producing tumors or hyperandrogenic disorders.

This study found that high TSPEAR expression in colorectal cancer was associated with poor prognosis and correlated with various tumor and immune-related factors.

This case study reports the first Palestinian case of an ovarian steroid cell tumor with virilization in a young female, highlighting the challenges in diagnosis and varied chemotherapeutic responses.

This case report discusses a patient with VHL-associated paraganglioma, highlighting the importance of genetic testing and monitoring in those with VHL disease, due to high mutation penetrance and associated risks.

This study demonstrates that the trichohyalin gene is located at chromosomal region 1q21, where several other genes related to epidermal differentiation also map.