Highlights from Recent Cancer Literature
February 2014
in “
Cancer Research
”
TLDR Recent findings advanced understanding of cancer mechanisms and potential treatments.
The document highlighted several key findings in cancer research. Schramek and colleagues found that MYH9 acted as a tumor suppressor in squamous cell carcinomas by stabilizing p53. Studies by Viaud and Iida suggested that gut microbiota influenced cancer treatment outcomes, with antibiotics potentially reducing therapy effectiveness. Fantozzi's research linked epithelial-to-mesenchymal transition (EMT) to cancer stemness and tumor initiation through VEGFA-mediated angiogenesis. White and colleagues demonstrated that hair follicle stem cells were resistant to oncogenic signals during quiescence, with PTEN playing a crucial role. Lastly, Lubanska's study on glioma-initiating cells revealed that the protein SPY1 influenced stemness and cell division, impacting glioma prognosis.
