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Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Using steroids can increase the risk of heart problems.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Hibiscus rosa-sinensis may help treat various health issues and promote hair growth, but more research is needed for safety.

Teucrium polium extracts are non-toxic and effectively speed up wound healing.

Over 67 genes linked to ichthyosis help improve diagnosis and treatment.

Chitrak is a medicinal plant with health benefits like fighting microbes, reducing inflammation, and promoting hair growth, but it can be toxic and needs more research.

New guidelines stress early diagnosis and lifestyle changes to manage metabolic syndrome and prevent complications.

Eating less and exercising more, with personalized diet plans and realistic goals, can lead to weight loss and better health, but more research is needed for long-term success.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

Early treatment of acne is crucial to prevent scarring and psychological effects.

The document concludes that managing PCOS requires a comprehensive approach, including lifestyle changes and medication, to improve symptoms and reduce health risks.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Plumbago zeylanica has valuable medicinal properties but needs sustainable cultivation methods.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Retinoids are effective for skin conditions like severe acne and psoriasis but must be used with caution due to potential side effects and risks during pregnancy.

The document concludes that accurate diagnosis and management of PCOS are crucial due to its associated health risks.

PCOS increases the risk of heart disease and type 2 diabetes in women.

Early-onset hair loss in young males is linked to a higher risk of metabolic syndrome.