September 2024 in “Dokumentenrepositorium der RUB (Ruhr University Bochum)” This study found that patients with higher baseline monocyte counts (\(\geq\) 925/\(\mu\)l) were significantly more likely to see treatment failure with adalimumab for hidradenitis suppurativa.
January 2024 in “Biomaterials Research” This study found that human hair follicle dermal papilla cells cultivated as 3D spheroids in hexanoyl glycol chitosan-coated dishes formed hair-like structures, with minoxidil enhancing growth, and successfully integrated into artificial skin models, suggesting advancements for hair loss treatments and skin restoration therapies.
7 citations
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August 2008 in “Immunogenetics” A gene mutation in mice causes increased mast cells and disorganized hair follicles in their skin.
March 2025 in “ACS Applied Materials & Interfaces” This study found that using an ultrasound hollow microneedle array enhanced transdermal delivery of finasteride, accelerating hair regrowth in mice with androgenetic alopecia compared to other delivery methods.
4 citations
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January 2017 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” This study identified two distinct VDR gene mutations among Lebanese families with hereditary vitamin D-resistant rickets, noting varied treatment responses and promising outcomes despite severe phenotypes.
August 2022 in “Frontiers in genetics” This study identified a novel bi-allelic missense variant in the DSC3 gene linked to severe Hypotrichosis with Recurrent Skin Vesicles in a Saudi child, supporting its role in the condition.
July 2024 in “JAAD Case Reports” This source reports that while effective treatments for hereditary hypotrichosis simplex have been limited, recent studies show promising results using interventions such as minoxidil, topical gentamicin, and platelet-rich plasma injections.
1 citations
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September 2023 in “Research Square (Research Square)” This study found that heart-inspired hollow hydrogel-based scaffolds enhanced regenerative capability in osteoporotic bone defects and increased cell number when using a mechanical-assisted post-bioprinting strategy.
5 citations
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July 2017 in “International journal of endocrinology and metabolism/International journal of endocrinology and metabolism.” This study described the clinical and genetic features of two Iranian siblings with hereditary vitamin D resistant rickets, identifying a specific VDR gene mutation contributing to their symptoms.
January 2023 in “Brazilian Journals Editora eBooks” HPLC may detect prediabetes and diabetes earlier than Immunoturbidimetry because it shows higher A1c levels.
November 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study developed a new method using ultrahigh-power sonication and mass spectrometry to improve protein extraction from hair shafts, identifying 239 differentially expressed proteins related to fetal growth restriction, which were validated as potential noninvasive biomarkers for perinatal diagnostics.
33 citations
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October 2005 in “Journal of Investigative Dermatology” A specific gene mutation causes sparse, brittle hair in a family.
March 2026 in “Journal of the American Academy of Dermatology” Hair diameter diversity could improve androgenetic alopecia assessment and treatment planning.
61 citations
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April 2021 in “Frontiers in Medicine” This study found that hidradenitis suppurativa significantly impaired quality of life in German patients, with severity linked to skin and certain extra-cutaneous changes, but not reduced by surgical or conventional medicamentous treatments.
1 citations
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August 2024 in “Lasers in Surgery and Medicine” This study observed that calcium hydroxylapatite can be successfully incorporated and retained in the dermis for at least six weeks after fractional laser treatment, with new collagen forming around it.
179 citations
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May 1982 in “The Journal of clinical investigation/The journal of clinical investigation” This study found that plasma 3 alpha-diol glucuronide was markedly elevated in women with idiopathic hirsutism, suggesting it may be a marker of peripheral androgen action.
5 citations
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October 2012 in “Australian veterinary journal” This report describes two South Australian Poll Hereford calves with a syndrome of congenital dyserythropoietic anaemia, dyskeratosis, and progressive alopecia, observing specific blood and bone marrow abnormalities.
86 citations
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June 1998 in “Journal of Investigative Dermatology” This study found that mutations in the hairless gene in mice disrupt hair follicle integrity during catagen, leading to baldness due to disintegrating epithelial structures and loss of normal dermal papilla.
7 citations
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August 2019 in “JAAD Case Reports” This article reviews the potential relationship between serum amyloid A and hidradenitis suppurativa, highlighting genetic influences, but reports no new clinical findings.
6 citations
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April 2013 in “British Journal of Dermatology” This article reviews various histological features of hidradenitis suppurativa and proposes discrepancies with previous nomenclature, reporting no new clinical findings; the authors highlight the need for revised understanding.
21 citations
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January 2006 in “Hormone Research in Paediatrics” In this case study, a girl with hereditary vitamin D resistant rickets had a novel mutation in the VDR gene that affected hair cycling without causing total alopecia, suggesting ligand-independent VDR function in hair cycling.
December 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This mini review discusses insights into the pathogenesis of hidradenitis suppurativa, highlighting genetic mutations, autoinflammation, and the effectiveness of biologics, and introduces the concept of autoinflammatory keratinization disease, without reporting new clinical results.
April 2024 in “JMR. Journal of molecular recognition/Journal of molecular recognition” This study found that hydrophilic carbon dots (Lys-CA-CDs) induced bovine serum albumin to form more wormlike fibrils, while inhibiting hen egg white lysozyme from forming hair-like fibrils.
1 citations
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June 2006 in “Experimental dermatology” This article reviews possible pathogenesis scenarios for hidradenitis suppurativa and emphasizes the need for focused research on the innate immune system of hair follicles to better understand the disease.
41 citations
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May 2024 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” This guideline outlines therapies for hidradenitis suppurativa/acne inversa, noting that oral tetracyclines, clindamycin, and surgical options are important for treatment, with adalimumab, secukinumab, and bimekizumab also approved.
11 citations
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December 2013 in “Clinical and experimental dermatology” This study reports a case of a child with congenital skin fragility, alopecia, and cardiomyopathy due to compound heterozygous mutations in the DSP gene causing desmoplakin deficiency.
June 2006 in “Experimental dermatology” This paper reviews potential animal models for studying hidradenitis suppurativa, specifically suggesting that certain mouse models with genetic mutations might be useful, but it reports no new experimental findings.
30 citations
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October 2009 in “Journal of Veterinary Internal Medicine” This report describes a unique case of hereditary vitamin D-resistant rickets (HVDRR) in a dog, caused by a VDR gene mutation resulting in severe hypocalcemia and bone issues, which presented with symptoms similar to those observed in humans.
12 citations
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May 2003 in “Journal of dermatological science” This study found that the heat shock cognate protein Hsc70 was differentially expressed by dihydrotestosterone treatment in SV40-transformed dermal papilla cells, suggesting its involvement in androgen action on these cells.
10 citations
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June 2023 in “Preprints.org” This review discusses transdermal drug delivery using hydrogel-forming microneedles and highlights their potential and challenges for clinical application, but it reports no new clinical findings.