Congenital Dyserythropoietic Anemia and Dyskeratosis in Australian Poll Hereford Calves

October 2012 in “ Australian veterinary journal ”

AE Kessell, DM Hanshaw, JW Finnie, P Nosworthy

congenital dyserythropoietic anaemia dyskeratosis progressive alopecia hyperkeratosis apoptosis CDA hair loss

TLDR Two Australian Poll Hereford calves had severe anaemia, abnormal red blood cells, and skin issues.

The document reported on two Poll Hereford calves from South Australia exhibiting congenital dyserythropoietic anaemia (CDA) with dyskeratosis and progressive alopecia, a syndrome previously noted in Canada and the USA. The calves showed severe anaemia with abnormal nucleated red blood cells in peripheral blood and numerous rubricytes and metarubricytes with distinctive nuclear ultrastructure in the bone marrow. They were born with wiry hair coats and developed a progressively 'dirty-faced' appearance due to hyperkeratosis and dyskeratosis (apoptosis).

View this study on onlinelibrary.wiley.com →

Discuss this study in the Community →

Related Community Posts Join

6 / 11 results

community Finasteride and Dutasteride results compilation thread

in Finasteride/Dutasteride 82 upvotes 3 weeks ago

Combining finasteride and dutasteride may enhance hair regrowth by targeting different enzymes, with positive results reported. Minoxidil, both oral and topical, is also used to improve effectiveness.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Stopping Dutasteride to have a baby

in Finasteride/Dutasteride 73 upvotes 6 days ago

A user plans to stop Dutasteride to conceive a child, seeking advice on hair maintenance. Suggestions include switching to Finasteride, but many emphasize prioritizing child safety.

community I will never more buy any hairloss traitements in public pharmacy

in Minoxidil 420 upvotes 1 month ago

A user was embarrassed by a pharmacist's loud mention of "minoxidil" for hair loss, sparking a discussion on the stigma and unprofessionalism. Users suggested online purchases or different pharmacies for privacy and reassured that most people don't notice others' purchases.

community I was on 2.5 mg oral minoxidil

in Progress Pictures 468 upvotes 4 months ago

User took 2.5 mg oral minoxidil, saw hair growth but stopped due to excessive body hair. Recently started finasteride and plans to update progress.

community Dutasteride Literally Saves Your Hair

in Finasteride/Dutasteride 96 upvotes 5 months ago

Dutasteride significantly reduces scalp DHT levels and can save hair, though shedding is part of the process. Some users report success with dutasteride, while others struggle despite using it along with finasteride and oral minoxidil.

Similar Research

5 / 1000+ results

research Congenital and Hereditary Skin Diseases in Bovines

January 2018

Bovines can have rare inherited skin diseases with specific symptoms like hair loss, fragile skin, and abnormal porphyrin buildup.

research Alopecia in Belgian Blue Crossbred Calves: A Case Series

November 2019 in “BMC veterinary research”

The hair loss in Belgian Blue crossbred calves was caused by a diet issue, not by disease or infection.

research Hypotrichosis Congenita (KRT71 Mutation) in Hereford Cattle in Uruguay

January 2023 in “Pesquisa Veterinária Brasileira”

A KRT71 mutation in Hereford cattle in Uruguay causes thin, curly hair and scaly skin.

research Abstracts From The 55th European Society Of Human Genetics Conference: E-Posters

1 citations, May 2023 in “European Journal of Human Genetics”

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

research 20th Annual Symposium of the British Society of Pediatric Dermatology, 11-12 November 2005, Newcastle Upon Tyne, UK

June 2006 in “British Journal of Dermatology”

The document reports unique growth lines in a child after Stevens-Johnson syndrome, skin reaction from parsnips and sun in a girl, and itchy skin with xanthomas in a boy with Alagille syndrome.