Isotretinoin-Induced Hair Growth in a Case of Hereditary Hypotrichosis Simplex of the Scalp: A Promising Therapeutic Approach

    July 2024 in “ JAAD Case Reports ”
    Almuntsrbellah Almudimeegh, Khalid Nabil Nagshabandi
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    TLDR Isotretinoin may effectively treat hereditary hypotrichosis simplex, a rare hair loss condition.
    A recent case study highlights the potential of isotretinoin as a therapeutic approach for hereditary hypotrichosis simplex (HHS), a rare genetic condition characterized by reduced hair follicle size leading to insufficient hair length and density. Historically, treatment options for HHS have been limited, but recent interventions like minoxidil, gentamicin, and platelet-rich plasma have shown promise. This case suggests isotretinoin could be a new effective treatment, offering hope for patients with this challenging condition.
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      community Isotretinoin and Tretinoin difference

      in Product  2 upvotes 1 week ago
      Isotretinoin and tretinoin are different; isotretinoin can cause hair loss and has more side effects. Tretinoin may affect minoxidil absorption, and users suggest waiting before applying minoxidil.

      community Which retinoid for better min absorption?

      in Product  4 upvotes 2 months ago
      User is on vacation in Greece and wants to buy tretinoin or isotretinoin to improve Minoxidil absorption. They are considering isotretinoin since it is available over-the-counter in Greece but requires a prescription back home.

      community Dut/Minox/Needling to Dut/Oral Minox/Tretinoin/Needling

      in Minoxidil  3 upvotes 6 months ago
      The user had been using Minoxidil and Dutasteride with micro-needling but experienced hair loss after switching Minoxidil brands. Their doctor prescribed oral Minoxidil and Tretinoin, but the pharmacist suggested isotretinoin might be a more cost-effective alternative.

      community Seborrheic dermatitis - can it cause long-term shedding (or telogen effluvium)?

      in Advice  6 upvotes 4 years ago
      A user is experiencing significant hair loss and scalp issues despite using Minoxidil, finasteride, and RU58841 since 2017. They switched to oral Minoxidil and are now on isotretinoin and topical corticosteroids for seborrheic dermatitis but continue to lose hair and seek advice on whether inflammation or treatment changes are the cause.

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