Isotretinoin-Induced Hair Growth in a Case of Hereditary Hypotrichosis Simplex of the Scalp: A Promising Therapeutic Approach

    September 2024 in “ JAAD Case Reports
    Almuntsrbellah Almudimeegh, Khalid Nabil Nagshabandi
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    TLDR Isotretinoin may effectively treat hereditary hypotrichosis simplex, a rare hair loss condition.
    A recent case study highlights the potential of isotretinoin as a therapeutic approach for hereditary hypotrichosis simplex (HHS), a rare genetic condition characterized by reduced hair follicle size leading to insufficient hair length and density. Historically, treatment options for HHS have been limited, but recent interventions like minoxidil, gentamicin, and platelet-rich plasma have shown promise. This case suggests isotretinoin could be a new effective treatment, offering hope for patients with this challenging condition.
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