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Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.

Ethosomes improve finasteride delivery through skin for hair loss treatment.

An imbalanced gut and lack of biotin can cause hair loss in mice.

Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

Minoxidil boosts hair growth by activating PGHS-1.

Procyanidin compounds from grape seeds were found to significantly increase mouse hair growth.

Wnt10b overexpression can regenerate hair follicles, possibly helping treat hair loss and alopecia.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

Shen-Min, a hair growth supplement, likely caused acute hepatitis in a woman, improving after she stopped taking it.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

TRH stimulates human hair growth and extends the hair growth phase.

S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

β-Catenin signaling is involved in brain cell growth after injury and could be a therapy target.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Human hair follicles can make and process prostaglandins, which may affect hair growth.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Conductive hydrogels show promise for medical uses like healing wounds and tissue regeneration but need improvements in safety and stability.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.