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The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Hair follicles can help wounds heal faster and this knowledge could be used to treat chronic skin ulcers, with a potential use of a special stem cell hydrogel to enhance healing.

Microneedles with enhancer effectively promote hair growth and increase hair density.

Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.

Southeast Asian herbs show promise for skin and hair care, but more research is needed to confirm their effectiveness in cosmetics.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

pH changes are crucial for root hair growth because they affect enzymes and proteins that control the cell wall and growth.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

Scalp cooling can prevent chemotherapy-induced hair loss, and certain treatments can speed up hair regrowth, but more research is needed for better treatments.

Chemotherapy can cause various skin problems, and recognizing them helps improve patient care.

Different soft tissue fillers can cause various skin reactions; biodegradable fillers are safer and non-biodegradable ones like silicone can lead to long-term problems.

Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.

Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.

The document concludes that better understanding the wound microbiome can improve chronic wound care by preserving helpful bacteria and targeting harmful ones.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Acne is caused by multiple factors including oil production, bacteria, inflammation, and possibly diet and environment.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

New therapies are being developed that target integrin pathways to treat various diseases.

Some skin conditions, like psoriasis and early-onset baldness, may indicate metabolic syndrome, and others are linked to diabetes risk and cardiovascular issues.

Women with PCOS have similar bone density to healthy women, but those who are obese have higher bone density at some body sites.

Zinc is crucial for skin health and treating various skin disorders.

PRP and PRF show promise for hair growth but need more research for consistent and safe use.

FKBP10 and FBN2 are key proteins for hair growth in cashmere goats.