19 citations,
November 1993 in “Mammalian Genome” A gene mutation in mice causes permanent hair loss and skin issues.
8 citations,
January 2007 in “International journal of experimental pathology” Hairless HRS/J mice resist Bacillus anthracis skin infections due to high numbers of immune cells, not because they lack hair follicles.
78 citations,
November 2005 in “Endocrinology” Hairless protein can block vitamin D activation in skin cells.
5 citations,
February 1981 in “Experientia” A new gene causes hairlessness and skin cysts in rats.
4 citations,
January 1996 in “British journal of dermatology/British journal of dermatology, Supplement” Mexican hairless dogs can help test new skin treatments.
126 citations,
October 1998 in “Experimental Dermatology” The hr gene is crucial for skin and hair health, with mutations causing hair disorders.
3 citations,
March 2010 in “Dermatologica Sinica” A Taiwanese patient had hair loss and skin bumps without the usual gene mutation, suggesting other genetic factors might be involved.
13 citations,
November 2013 in “Journal of Endocrinology/Journal of endocrinology” Vitamin D receptor helps control hair growth genes in skin cells.
10 citations,
January 2010 in “Veterinary pathology” A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.
7 citations,
November 2011 in “Skin Research and Technology” The study found a specific pattern of uneven melanin distribution on balding scalps that could help understand skin diseases caused by light exposure.
2 citations,
December 2019 in “Archives of Craniofacial Surgery” Using a method of stretching skin multiple times can help cover large bald spots on the scalp, but it takes a long time and isn't good for kids.
Vitamin D is made by the skin, helps control various body functions, and affects skin health and immunity.
January 2012 in “Human health handbooks” The skin produces and uses vitamin D for bone health, cell growth, and immune function.
185 citations,
December 2011 in “Molecular and cellular endocrinology” Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.
6 citations,
June 2016 in “Journal of cellular biochemistry” The Hr protein binds to DNA, interacts with p53, and affects cell cycle genes.
1 citations,
July 2022 in “Experimental dermatology” The SHJH hr mice with a mutated Hr gene show signs of faster skin aging due to poor antioxidative protection.
Hairless mammals evolved quickly in both gene and non-gene areas related to skin and hair.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.
158 citations,
August 2011 in “Reviews in endocrine and metabolic disorders” Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.
8 citations,
February 2005 in “International Journal of Cosmetic Science” Applying a special soy milk extract on skin can make it more elastic and hydrated.
7 citations,
August 2017 in “PloS one” Key genes linked to hair growth and cancer were identified in hairless mice.
June 2017 in “International Journal of Periodontics & Restorative Dentistry” Using skin grafts from behind the ear for oral surgery in two patients with jaw injuries led to successful healing and good results.
April 1955 in “Archives of pediatrics & adolescent medicine” Children's skin diseases need special care and treatment.
56 citations,
February 2012 in “Developmental biology” Sostdc1 controls the size and number of hair and mammary gland structures.
10 citations,
January 2021 in “Journal of Ginseng Research” Red ginseng oil may help grow hair and protect skin from UVC light.
12 citations,
February 2008 in “Journal of The American Academy of Dermatology” Combining skin tissue pathology with genetics has greatly improved the diagnosis and understanding of certain skin diseases.
September 2016 in “Journal of Dermatological Science” A gene mutation worsens skin irritation in mice due to a lack of certain fats.
September 2022 in “IP Indian journal of clinical and experimental dermatology” An 8-year-old girl has a rare genetic disorder causing complete, irreversible hair loss and skin bumps.
2 citations,
November 2017 in “Journal of Cosmetic Dermatology” Injecting platelet-rich plasma under the skin significantly improves hair growth and quality without harmful effects.
December 2023 in “Journal of General Procedural Dermatology and Venereology Indonesia” A 61-year-old Filipino man had a skin condition that looked like another disease, making diagnosis difficult.