Search

everythinglearnresearchcommunity

for

Search:↓

Scientists developed a system to study human hair growth using skin cells, which could help understand hair development and improve skin substitutes for medical use.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

Scalp biopsies from dermatomyositis patients show chronic hair loss without scarring, with mucin and blood vessel changes being very common.

A 5-year-old Akita with a rare skin condition improved significantly after treatment.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Flamena, a liposomal mix, helps skin heal better after a chemical burn.

The study found that a one-step antibody method is better than the LSAB method for accurately studying hair follicle structures without false positives.

PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

Sweat glands and hair follicles are structurally connected within a specific layer of skin fat.

Keratin-associated proteins have ancient origins and were used for different purposes before being adapted for hair in mammals.

The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.

Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.

Some patients with a type of skin lymphoma can experience a rare, non-scarring hair loss that looks like another hair loss condition but has distinct features.

Stem cells from whiskers can be transplanted to stimulate hair growth.

Hair proteins have weak spots in their α-helical segments.

Special and immunohistochemical stains are not routinely needed for diagnosing hair disorders.

Some hair protein genes evolved early and were adapted for use in hair follicles.

Cathepsin L is essential for normal hair growth and development.

Less AgNOR protein production is linked to hair loss.

TGFβ signaling prevents sebaceous gland cells from producing fats.

New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.

Pioglitazone use was linked to hair regrowth in a patient with permanent hair loss from cicatricial alopecia.

Stopping S100A3 activity slows down hair growth in mice.

Topical treatments led to hair regrowth in a man with linear morphea.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.