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People with allergies or high eosinophil levels have a higher chance of severe hair loss from alopecia areata, and sudden hair loss can indicate chronic graft-versus-host disease.

AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.

Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.

Certain genetic changes in the LSS gene cause a rare skin and hair condition.

A new mutation in the K6b gene caused a girl's late-appearing nail condition.

Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

Hair in mammals likely evolved from glandular structures, not scales.

Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.

Skin issues can indicate immune system problems.

Equisetum debile extracts may help with skin whitening, anti-wrinkle, and anti-hair loss treatments.

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

Transglutaminase activity is important for skin and is found in both mammals and birds.

Skin side effects from cancer treatments can lead to changes in therapy and are common, with nail changes being the most frequent.

Platelet-rich plasma shows potential for hair loss and skin rejuvenation but needs more research for widespread use.

Keratoacanthoma comes from hair follicle cells.

Tofacitinib improved hair loss and skin symptoms in a patient after secukinumab caused hair loss.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

New insights show Lichen Planopilaris is a rare, scarring hair loss condition, hard to treat, mainly affecting middle-aged women, and significantly impacts mental health.

Different types of hair loss in lupus need careful diagnosis for proper treatment.

Dermoscopy is useful for many health professionals, not just dermatologists, in improving skin condition diagnoses and reducing unnecessary biopsies.

NK cells play a role in skin diseases like eczema and psoriasis.

A horse with severe hair loss was diagnosed with alopecia areata and a yeast infection.

Skin abnormalities can indicate immunodeficiency due to shared origins with the immune system.

Toxic Shock Syndrome mainly affects menstruating women, can recur, and is linked to staph bacteria, with rapid treatment being crucial.

Nanoemulsion-based drug delivery systems are versatile and have potential for treating various medical conditions and improving vaccines.

The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.