research The Skin and Subcutaneous Tissues: Conditions, Diagnosis, and Systemic Implications
The document concludes that skin and nail changes can indicate various underlying health conditions.
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research A Human Prenatal Skin Cell Atlas Reveals Immune Cell Regulation of Skin Morphogenesis
Immune cells are essential for early hair and skin development and healing.
research Comparative Evaluation Between Two Nutritional Supplements in the Improvement of Telogen Effluvium
One supplement improved hair loss and quality faster and more effectively than the other in treating telogen effluvium.
research Diseases of the Hair and Nails
Stress, nutritional issues, and chronic diseases can cause hair loss, and nail changes may signal internal diseases; treatment focuses on the underlying cause.
research The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target During Hair Follicle and Nail Differentiation
HOXC13 is essential for hair and nail development by regulating Foxn1.
research Comparative Spatial Transcriptomic and Single-Cell Analyses of Human Nail Units and Hair Follicles Show Transcriptional Similarities between the Onychodermis and Follicular Dermal Papilla
Human nails and hair follicles have similar gene activity, especially in the cells that contribute to their growth and development.
research Effect of Dietary Methylsulfonylmethane Supplementation on Growth Performance, Hair Quality, Fecal Microbiota, and Metabolome in Ragdoll Kittens
MSM supplementation in kittens improves hair quality and growth rate without harming their health.
research The Formulation and In-Vitro Evaluation of WS Biotin, a Novel Encapsulated Form of D-Biotin with Improved Water Solubility for Hair and Skin Treatment Applications
WS Biotin, a new form of D-Biotin, improves water solubility and shows potential for hair and skin care without being toxic at low levels.
research Topical Delivery of Atraric Acid Derived From Stereocaulon Japonicum With Enhanced Skin Permeation and Hair Regrowth Activity for Androgenic Alopecia
AA–TF#15 significantly promotes hair regrowth and could be an effective treatment for androgenic alopecia.
research Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles
Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
research Penetration of Drugs Through Skin: A Complex Rate-Controlling Membrane
The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
research Zinc Deficiency Associated with Hypothyroidism: An Overlooked Cause of Severe Alopecia
Zinc supplements may be needed to treat hair loss in hypothyroidism.
research Non-Invasive Human Skin Transcriptome Analysis Using mRNA in Skin Surface Lipids
The conclusion is that analyzing RNA from skin oils is a promising way to understand skin diseases.
research Case Series of Selenium Toxicity from a Nutritional Supplement
Excessive selenium from a supplement caused toxicity but patients recovered with care.
research Organization and Expression of Hair Follicle Genes
Hair growth is controlled by specific gene clusters and proteins, and cysteine affects hair gene expression in sheep.
research Evaluating Hair Growth Promoting Effects of Candidate Substances: A Review of Research Methods
The document concludes that while lab results for hair growth promotion are promising, human trials are needed and better testing methods should be developed.
research Efficacy and Tolerability of Hairgain in Individuals with Hair Loss: A Placebo-Controlled, Double-Blind Study
Hairgain® significantly increased hair growth and was well-tolerated by individuals with hair loss.
research Establishing and Prioritizing Research Questions for the Prevention, Diagnosis, and Treatment of Hair Loss (Excluding Alopecia Areata): The Hair Loss Priority Setting Partnership
The study identified the top 10 most important areas for future hair loss research.
research Oral Zinc Sulphate in Treatment of Patients with Thallium Poisoning: A Clinical Therapeutic Trial
Oral zinc sulphate is an effective and safe treatment for thallium poisoning, especially for skin and hair symptoms.
research Serum Biotin and Zinc in Male Androgenetic Alopecia
Low zinc and biotin levels linked to male hair loss; supplements may help.
research Effects of a Combination of Arginine Silicate Inositol Complex and a Novel Form of Biotin on Hair and Nail Growth in a Rodent Model
The combination of Arginine Silicate Inositol Complex and a new form of Biotin improved hair and nail growth in rats.
research Trachyonychia Associated with Alopecia Areata and Secondary Onychomycosis
An 8-year-old girl had nail and hair issues that improved without specific treatment, but fungal nail infection was hard to cure.
research The Role of Vitamins and Minerals in Hair Loss: A Review
Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.
research Use of Vitamins and Minerals in the Treatment of Hair Loss: A Cross-Sectional Survey Among Dermatologists in Saudi Arabia
Many dermatologists in Saudi Arabia recommend vitamins and minerals for hair loss, often based on personal experience rather than strong evidence.
research Differentiation of Mouse Induced Pluripotent Stem Cells into a Multipotent Keratinocyte Lineage
Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.
research Cutaneous Toxicities of New Targeted Cancer Therapies: Must Know for Diagnosis, Management, and Patient-Proxy Empowerment
New targeted cancer drugs can cause skin side effects, and managing them requires patient education and timely care.
research Specific Ectodermal Enhancers Control the Expression of Hoxc Genes in Developing Mammalian Integuments
The HoxC gene cluster and its enhancers are essential for developing hair and nails in mammals.
research Alopecia Areata Incognita in Cronkhite-Canada Syndrome
The report suggests that hair loss in Cronkhite-Canada syndrome may be caused by alopecia areata incognita, as shown by a patient's improvement with treatment.
research Trichohyalin-Like Proteins Have Evolutionarily Conserved Roles in the Morphogenesis of Skin Appendages
Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.
research Delayed Cutaneous Wound Healing and Aberrant Expression of Hair Follicle Stem Cell Markers in Mice Selectively Lacking Ctip2 in Epidermis
Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.