30 citations,
May 2016 in “Expert Opinion on Biological Therapy” New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.
253 citations,
April 2014 in “Drugs” Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.
80 citations,
September 2007 in “Cell Cycle” Stem cells in hair follicles can become various cell types, including neurons.
35 citations,
August 2021 in “npj Regenerative Medicine” Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
29 citations,
March 2012 in “Stem Cell Research & Therapy” Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.
25 citations,
April 2021 in “The EMBO Journal” Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
15 citations,
January 2019 in “Experimental Dermatology” Lanyu pigs show that partial-thickness wounds can partially regenerate important skin structures, which may help improve human skin healing.
7 citations,
January 2023 in “Frontiers in cell and developmental biology” Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.
August 2019 in “International journal of current microbiology and applied sciences” Young dogs in Odisha with dermatitis are most often infected by Microsporum fungus, and Miconazole is the most effective treatment.
117 citations,
April 2008 in “Developmental biology” Ectodysplasin inhibits Wnt signaling to help form hair follicles.
33 citations,
January 2018 in “The International Journal of Developmental Biology” Cell aging can be both good and bad for tissue repair.
39 citations,
October 2018 in “Aesthetic surgery journal” Injectables can feminize or masculinize a transgender person's face, but more research is needed for best practices.
85 citations,
December 2017 in “Developmental Biology” Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
29 citations,
January 2021 in “Translational Psychiatry” The research suggests that Tourette syndrome is linked to both brain signaling and immune system pathways.
TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.
148 citations,
October 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice without the vitamin D receptor are more prone to UV-induced skin tumors.
8 citations,
January 2020 in “Skin appendage disorders” Saw palmetto supplements may modestly improve hair regrowth with few side effects, but more research is needed.
215 citations,
November 2006 in “Journal of The American Academy of Dermatology” Dutasteride more effective for hair growth, but has more side effects than finasteride.
25 citations,
May 2019 in “Cosmetics” 18-MEA and cationic surfactants can restore and maintain hair's hydrophobic nature, improving its beauty and feel.
January 2023 in “Vìsnik problem bìologìï ì medicini” Androgenic alopecia causes hair follicle degradation and skin restructuring, but some hair elements remain.
66 citations,
July 2015 in “Journal of Molecular Biology” The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
8 citations,
July 2019 in “Cell Proliferation” Researchers found a way to turn skin cells into cells that can grow new hair.
60 citations,
April 2012 in “Physiology” The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
88 citations,
August 2008 in “Development” BMP2 and BMP7 have opposite roles in feather formation.
64 citations,
July 2016 in “Cold Spring Harbor Perspectives in Medicine” The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
25 citations,
August 2007 in “Molecular Therapy” Researchers found a safe and effective way to pick genetically modified skin cells with high growth potential using CD24.
1 citations,
June 2022 in “PubMed” Alopecia causes hair loss and should be treated early, especially scarring types where hair cannot regrow.
86 citations,
August 2014 in “Journal of The American Academy of Dermatology” To diagnose hair loss, use a systematic approach including history, exams, and tests.
68 citations,
August 2012 in “Journal of the American Academy of Dermatology” Dermatoscopy is a useful tool for diagnosing hair disorders and can help choose samples for more detailed analysis.
30 citations,
August 1983 in “Pediatric Clinics of North America” Most hair loss in children is caused by a few common conditions, and it's important to diagnose these properly and support the child's mental health.