Typical Morphological Characteristics of the Skin Structure of the Hair Part of the Normal Human Head and with Hair Loss

    О. О. Tykhonova, O. О. Sherstyuk, Ya. A. Tarasenko, V. P. Bilash, S. I. Serbin, S. O. Dubina, O. T. Tkachenko
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    TLDR Androgenic alopecia causes hair follicle degradation and skin restructuring, but some hair elements remain.
    The study examines the structural organization of scalp skin under normal conditions and during androgenic alopecia. It finds that thicker hair, with deeper root bulbs, is more resistant to alopecia. Androgenic alopecia leads to the degradation of intradermal hair follicles, increased formation of aggregate follicles, and replacement of degenerating follicles with connective tissue. Despite complete hair loss, germinative epithelial elements remain, forming thin abortive hairs within sebaceous glands. The study concludes that androgenic alopecia results in compensatory skin restructuring, including increased blood vessel growth and higher sebaceous gland concentration, which may inform future dermatological treatments.
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