research The Shifting Landscape of Disease-Modifying Therapies for Relapsing Multiple Sclerosis
New treatments for relapsing multiple sclerosis are more effective and convenient but have higher risks of serious side effects.
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research Scientific Precision in Titles of Research Papers Published in Three Dermatology Journals
Many research paper titles in dermatology journals lack scientific precision.
research Therapeutic, Prophylactic, and Functional Use of Probiotics: A Current Perspective
Probiotics show promise for health benefits but need more research to understand how they work.
research The Possible Implication of the S250C Variant of the Autoimmune Regulator Protein in a Patient with Autoimmunity and Immunodeficiency: In Silico Analysis Suggests a Molecular Pathogenic Mechanism for the Variant
The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.
research Recommendations From The 2023 International Evidence-Based Guideline For The Assessment And Management Of Polycystic Ovary Syndrome
The 2023 guideline for PCOS suggests using updated diagnostic criteria, assessing related health risks, and recommends lifestyle changes and specific treatments for symptoms and fertility issues.
research Functional Analysis of VDR Gene Mutation R343H in a Child with Vitamin D-Resistant Rickets with Alopecia
The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.
research Membranous Nephropathy and Lupus-Like Syndrome After Hematopoietic Cell Transplantation: A Case Report
A man developed autoimmune issues after a transplant, improved with treatment, but died from leukemia relapse.
research Research Techniques Made Simple: Optical Clearing and Three-Dimensional Volumetric Imaging of Skin Biopsies
3D imaging of skin biopsies offers better accuracy but is time-consuming and can't clear melanin.
research The Progress in Bioprinting and Its Potential Impact on Health-Related Quality of Life
Bioprinting could greatly improve health outcomes but faces challenges like material choice and ensuring long-term survival of printed tissues.
research Crystal Structure of Steroid Reductase SRD5A Reveals Conserved Steroid Reduction Mechanism
The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.
research Benign Cutaneous Eruptions After Transplantation
Transplant patients often get skin problems, with treatments varying by condition.
research Recommendations From The 2023 International Evidence-Based Guideline For The Assessment And Management Of Polycystic Ovary Syndrome
The 2023 guideline advises a detailed approach for PCOS, focusing on early detection, lifestyle and medical treatments, and managing health risks.
research Recent Advances in Electrospun Nanofibers for Wound Healing
New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.
research Steroids And Steroid-Like Compounds
Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.
research Generation and Characterization of Rat Liver Stem Cell Lines and Their Engraftment in a Rat Model of Liver Failure
Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.
research Omega 3 Fatty Acid-Enriched Nanoemulsion of Thiocolchicoside for Transdermal Delivery: Formulation, Characterization, and Absorption Studies
The new formulation improved the skin absorption of the drug Thiocolchicoside.
research Optimization of Menthol-Loaded Nanocapsules for Skin Application Using the Response Surface Methodology
Researchers created better skin-application menthol capsules that are stable, safe, and penetrate the skin quickly.
research Diet and Acne
Diet changes can help reduce acne by limiting certain hormones.
research Multi-Faceted Enhancement of Full-Thickness Skin Wound Healing by Treatment with Autologous Micro Skin Tissue Columns
Using micro skin tissue columns improves skin wound healing and reduces scarring.
research Effect of Tocopheryl Polyethylene Glycol Succinate on the Percutaneous Penetration of Minoxidil from Water/Ethanol/Polyethylene Glycol 400 Solutions
Adding TPGS to minoxidil solutions can improve skin penetration and retention, especially in water and PEG 400-based solutions.
research Trends in Nanotechnology for Practical Applications
Nanotechnology is improving drug delivery and targeting, with promising applications in cancer treatment, gene therapy, and cosmetics, but challenges remain in ensuring precise delivery and safety.
research Contraindicated Use of 5-Alpha-Reductase Inhibitors in Women
The document concludes that women should not use 5-alpha-reductase inhibitors due to the risk of birth defects and limited effectiveness.
research Computational Screening of Repurposed Drugs and Natural Products Against SARS-CoV-2 Main Protease as Potential COVID-19 Therapies
Some existing drugs and natural products might work against COVID-19 by targeting the virus's main protease.
research The British Society for Rheumatology Guideline for the Management of Systemic Lupus Erythematosus in Adults
The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.
research Feline Atopic Dermatitis: A Retrospective Study of 45 Cases (2001–2012)
Cats with atopic dermatitis often have severe, year-round itching and respond well to certain treatments.
research A Flexible Fixed-Sequence Testing Method for Hierarchically Ordered Correlated Multiple Endpoints in Clinical Trials
The flexible fixed-sequence testing method allows for more effective evaluation of multiple goals in a clinical trial while controlling the risk of false positives.
research Skin Aging as a Mechanical Phenomenon: The Main Weak Links
Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.
research Experimental and Thermodynamic Analyses of Supercritical CO2 Solubility of Minoxidil as an Antihypertensive Drug
Minoxidil dissolves better in propylene glycol + water than in supercritical CO2.
research Elevated Serum Androstenedione Is Associated With a More Severe Phenotype in Women With Polycystic Ovary Syndrome
Higher androstenedione levels in women with PCOS are linked to more severe symptoms.
research Revisiting Hyper- and Hypo-Androgenism by Tandem Mass Spectrometry
The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.