Search

for
Search:

Did you mean hair keratin?

GlossaryKeratin

protein forming hair, nails, and skin's outer layer

Keratin is a type of protein that forms the structural foundation of hair, nails, and the outer layer of skin. It provides strength and protection, making these tissues resilient and less prone to damage. In hair, keratins are essential for maintaining its integrity and elasticity, and they play a crucial role in the hair's overall health and appearance.

Related Terms

Sort by

Research

30 / 1000+ results

Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity

research Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity

November 2023 in “Advanced Science”

A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.

research Hair Keratin KRT81 Is Expressed in Normal and Breast Cancer Cells and Contributes to Their Invasiveness

24 citations, April 2017 in “Oncology Reports”

The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.

research The Proteomic Profile of Hair Damage

20 citations, June 2012 in “British Journal of Dermatology”

Bleaching hair damages protein structure, especially keratin, leading to weakened hair.

research A Comparative Study of Materials Assembled from Recombinant K31 and K81 and Extracted Human Hair Keratins

2 citations, September 2020 in “Biomedical materials”

Recombinant keratin materials may better promote skin cell differentiation than natural keratin.

research In Vitro Assembly Properties of Human Type I and II Hair Keratins

12 citations, January 2014 in “Cell structure and function”

Different combinations of human hair keratins affect how hair fibers form.

research The Hair Follicle: An Underutilized Source of Cells and Materials for Regenerative Medicine

30 citations, March 2017 in “ACS biomaterials science & engineering”

Hair follicles are valuable for regenerative medicine and wound healing.

research Homo- and Heteropolymer Self-Assembly of Recombinant Trichocytic Keratins

13 citations, July 2017 in “Biopolymers”

Recombinant keratins can form useful structures for medical applications, overcoming natural keratin limitations.

research Mechanical and Biological Properties of Keratose Biomaterials

140 citations, August 2011 in “Biomaterials”

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

research To Grow or Not to Grow: Hair Morphogenesis and Human Genetic Hair Disorders

43 citations, December 2013 in “Seminars in Cell & Developmental Biology”

Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.

Transcriptional Profiling in Alopecia Areata Defines Immune and Cell Cycle Control Related Genes Within Disease-Specific Signatures

research Transcriptional Profiling in Alopecia Areata Defines Immune and Cell Cycle Control Related Genes Within Disease-Specific Signatures

61 citations, September 2010 in “Genomics”

The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.

In Silico Analysis of Gene Expression Data from Bald Frontal and Haired Occipital Scalp to Identify Candidate Genes in Male Androgenetic Alopecia

research In Silico Analysis of Gene Expression Data from Bald Frontal and Haired Occipital Scalp to Identify Candidate Genes in Male Androgenetic Alopecia

6 citations, September 2019 in “Archives of Dermatological Research”

Found 32 genes linked to male baldness, affecting hair growth and stress-related pathways.

research Contribution of Environmental Constituents in the Genomic Disruption of Cytokeratins

1 citations, July 2021 in “IntechOpen eBooks”

Environmental factors can cause mutations in skin proteins, leading to skin disorders.

Skin Physiology in Microgravity: A 3-Month Stay Aboard ISS Induces Dermal Atrophy and Affects Cutaneous Muscle and Hair Follicles Cycling in Mice

research Skin Physiology in Microgravity: A 3-Month Stay Aboard ISS Induces Dermal Atrophy and Affects Cutaneous Muscle and Hair Follicles Cycling in Mice

48 citations, May 2015 in “NPJ microgravity”

A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.

iTRAQ-Based Quantitative Proteomics Revealing the Therapeutic Mechanism of a Medicinal and Edible Formula YH0618 in Reducing Doxorubicin-Induced Alopecia by Targeting Keratins and TGF-β/Smad3 Pathway

research iTRAQ-Based Quantitative Proteomics Revealing the Therapeutic Mechanism of a Medicinal and Edible Formula YH0618 in Reducing Doxorubicin-Induced Alopecia by Targeting Keratins and TGF-β/Smad3 Pathway

June 2024 in “Heliyon”

YH0618 helps reduce chemotherapy-induced hair loss by targeting specific proteins and pathways.

research Trichoscopy in Hair Shaft Disorders

36 citations, August 2018 in “Dermatologic Clinics”

Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.

research Transcriptome Profiling and Differential Gene Expression in Canine Microdissected Anagen and Telogen Hair Follicles and Interfollicular Epidermis

7 citations, August 2020 in “Genes”

Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.

The Binding of Small Molecules and Polymers to Keratin and Their Effects on the Physicochemical and Surface Properties of Hair Fibers

research The Binding of Small Molecules and Polymers to Keratin and Their Effects on the Physicochemical and Surface Properties of Hair Fibers

7 citations, January 1981 in “Springer eBooks”

Certain small molecules and polymers can change hair's physical properties and how it feels by affecting the bonds within the hair.

research Identification of the Ovine Keratin-Associated Protein 22-1 (KAP22-1) Gene and Its Effect on Wool Traits

42 citations, January 2017 in “Genes”

The gene KAP22-1 affects wool yield and fiber shape in sheep.

research Mutations In AEC Syndrome Skin Reveal A Role For p63 In Basement Membrane Adhesion, Skin Barrier Integrity And Hair Follicle Biology

33 citations, February 2012 in “British Journal of Dermatology”

Mutations in the p63 gene affect skin adhesion, barrier integrity, and hair growth.

research Structural Hierarchy of Trichocyte Keratin Intermediate Filaments

15 citations, January 2018 in “Advances in experimental medicine and biology”

Keratin proteins are crucial for hair growth and structure.

research Diversity of Trichocyte Keratins and Keratin-Associated Proteins

16 citations, January 2018 in “Advances in experimental medicine and biology”

Hair and wool have diverse keratins and keratin-associated proteins.

research Congenital Hair Loss Disorders: Rare, But Not Too Rare

41 citations, November 2011 in “The Journal of Dermatology”

Some hair loss disorders are caused by genetic mutations affecting hair growth.

research Evolution of Trichocyte Keratins

18 citations, January 2018 in “Advances in experimental medicine and biology”

Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.

research Characterization of a 190-Kilobase Pair Domain of Human Type I Hair Keratin Genes

74 citations, October 1998 in “Journal of biological chemistry/The Journal of biological chemistry”

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

The Human Type I Keratin Gene Family: Characterization of New Hair Follicle Specific Members and Evaluation of the Chromosome 17q21.2 Gene Domain

research The Human Type I Keratin Gene Family: Characterization of New Hair Follicle Specific Members and Evaluation of the Chromosome 17q21.2 Gene Domain

70 citations, December 2004 in “Differentiation”

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

research Molecular Modeling of Hair Keratin/Peptide Complex: Using MM-PBSA Calculations to Describe Experimental Binding Results

14 citations, January 2012 in “Proteins”

Electrostatic interactions mainly stabilize the binding of peptides to hair keratin.

research A Mutation in the Type II Hair Keratin KRT86 Gene in a Han Family with Monilethrix

3 citations, February 2011 in “Journal of Biomedical Research/Journal of biomedical research”

A new mutation in the KRT86 gene was found to cause the hair disorder monilethrix in a Han family.

research A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth

192 citations, April 2019 in “ACS nano”

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

research Changing the Shape of Hair with Keratin Peptides

47 citations, January 2017 in “RSC Advances”

Keratin peptides can change hair shape gently without harsh chemicals.

research Keratin Network Modifications Lead to the Mechanical Stiffening of the Hair Follicle Fiber

40 citations, May 2016 in “Proceedings of the National Academy of Sciences of the United States of America”

Changes in keratin make hair follicles stiffer.