research First-In-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors
MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
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research Environmental and Cosmetic Factors in Hair Loss and Damage
Environmental and cosmetic factors, including heat, chemicals, and sun exposure, can cause hair loss and damage.
research Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells
A specific DNA region is crucial for Foxn1 gene expression in thymus cells but not in hair follicles.
research General Dermatology: Comprehensive Overview of Dermatological Conditions
The document explains various skin conditions and their treatments.
research Significance of Iron Status in Hair Loss in Women
Iron deficiency might contribute to hair loss in women.
research Sexual Hormones in Human Skin
Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.
research Evaluation of the Safety and Efficacy of Concentrated Growth Factors for Hair Growth Promotion in Androgenetic Alopecia Patients: A Retrospective Single-Center, Single-Arm Study
CGF injections may safely and effectively promote hair growth in androgenetic alopecia patients.
research Proliferative and Non-Proliferative Lesions of the Rat and Mouse Integument
The project created a standardized system for classifying skin lesions in lab rats and mice.
research Minoxidil And Its Use In Hair Disorders: A Review
Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.
research The Involvement of Elf5 in Regulating Keratinocyte Proliferation and Differentiation Processes in Skin
Elf5 controls skin cell growth and development, making it a potential target for skin treatments.
research A Practical Guide for the Study of Human and Murine Sebaceous Glands In Situ
The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.
research Therapeutic Potential of Adult Platelets and Cord Blood Platelets in Future Clinical Directions
Cord blood platelets may have promising future medical uses but need more research.
research Topical Application of Thymidine Dinucleotide to Newborn Mice Reduces and Delays Development of UV-Induced Melanomas
Putting thymidine dinucleotide on newborn mice's skin can delay and reduce skin cancer.
research Dermoscopy: Distinguishing Malignant Tumors From Benign
Dermoscopy greatly improves melanoma diagnosis and reduces unneeded surgeries.
research Can Dermal Delivery of Therapeutics Be Improved Using Thermoresponsive Nanogels?
Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.
research Cellular Therapeutics and Immunotherapies in Wound Healing – On the Pulse of Time?
Cellular and immunotherapies show promise for healing chronic wounds but need more research.
research Genetic Basis of Polycystic Ovary Syndrome
The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.
research Vascular Mechanisms in Laser Hair Removal
Laser hair removal might also work by damaging blood vessels around hair follicles.
research Growth and Viability of Liaoning Cashmere Goat Hair Follicles During the Annual Hair Follicle Cycle
Liaoning Cashmere goat hair follicles show synchronized growth patterns with lowest activity in May.
research Marine-Derived Bioactive Peptides in Self-Assembled Multifunctional Materials: Antioxidant and Wound Healing Properties
Peptides from oysters may safely and effectively heal skin wounds with less scarring.
research Ten Years of Injectable Platelet-Rich Fibrin
Injectable platelet-rich fibrin has improved healing and regeneration in various medical fields and can be more effective than previous treatments.
research Efficacy and Safety of Combined Microneedling Therapy for Androgenic Alopecia: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
Microneedling combined with other treatments significantly improves hair growth in people with hair loss and is safe.
research Hair Shaft Miniaturization Causes Stem Cell Depletion Through Mechanosensory Signals Mediated by a Piezo1-Calcium-TNF-α Axis
Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.
research Local Artemis Dysfunction May Be One Molecular Mechanism for Androgenetic Alopecia via Telomere Shortening
Artemis dysfunction might cause hair loss through telomere shortening.
research Secondary Cicatricial and Other Permanent Alopecias
The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.
research Rational Design of a Topical Androgen Receptor Antagonist for the Suppression of Sebum Production with Properties Suitable for Follicular Delivery
A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.
research Concentrated Growth Factor Therapy as Cosmetic Treatment in Discoid Lupus Erythematosus
CGF therapy may help hair regrowth and improve scars in DLE patients.
research The Ludwig Pattern of Androgenetic Alopecia Is Due to a Hierarchy of Androgen Sensitivity Within Follicular Units That Leads to Selective Miniaturization and a Reduction in the Number of Terminal Hairs Per Follicular Unit
Ludwig pattern hair loss in women results from varying sensitivity in hair follicles, causing fewer visible hairs.
research Advanced Skin Antisepsis: Application of UVA-Cleavable Hydroxyethyl Starch Nanocapsules for Improved Eradication of Hair Follicle-Associated Microorganisms
New UVA-responsive nanocapsules effectively kill microorganisms in hair follicles when activated by light.
research Optimization of Lipid-Based Nanoformulation for Cutaneous Targeting: Niosomes as Potential Candidates
Niosomes are the most effective at delivering drugs to the skin with minimal absorption into the body.