2 citations,
July 2022 in “Frontiers in Medicine” The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.
September 2024 in “Stem Cell Research & Therapy” HA-stimulated stem cell vesicles improved hair growth in male mice with androgenetic alopecia.
March 2024 in “Dermatology and therapy (Internet)” Genetic factors could lead to personalized treatments for hair loss.
August 2023 in “International Journal of Molecular Sciences” Human skin xenografting could improve our understanding of skin development, renewal, and healing.
2 citations,
September 2023 in “International journal of molecular sciences” Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
4 citations,
December 2022 in “International Journal of Molecular Sciences” Zinc is crucial for skin health and treating various skin disorders.
53 citations,
July 2018 in “Drug design, development and therapy” Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.
68 citations,
March 2002 in “Journal of pharmaceutical sciences” Nonionic liposomes are the best for delivering genes to skin cells.
December 2023 in “Communications biology” Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.
179 citations,
July 2016 in “Nature Reviews Molecular Cell Biology” Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
75 citations,
August 2018 in “Biochemical pharmacology” Targeting the skin's endocannabinoid system could help treat skin disorders.
1 citations,
April 2018 in “Journal of Investigative Dermatology” PRC1 is essential for proper skin development and stem cell formation by controlling gene activity.
April 2018 in “Journal of Investigative Dermatology” BMP signaling is important for skin color, affecting melanin production, pigment spread, and cell movement.
70 citations,
January 2014 in “International review of cell and molecular biology” Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
65 citations,
February 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Anti-acne medications may work by reducing the activity of a protein involved in acne development.
45 citations,
April 2018 in “Nature Reviews Urology” Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
32 citations,
March 2014 in “PLOS ONE” Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.
119 citations,
March 2020 in “Frontiers in Bioengineering and Biotechnology” Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
70 citations,
August 2020 in “Nanomaterials” Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.
32 citations,
February 2017 in “Oncotarget” Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.
22 citations,
October 2011 in “Bone” Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
24 citations,
April 2014 in “Oncotarget” Minoxidil can reduce functions related to androgen receptors.
5 citations,
July 2022 in “Orphanet journal of rare diseases” RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.
3 citations,
January 2020 in “Plastic and Aesthetic Research” Non-surgical procedures can help reduce wrinkles and stimulate skin repair by understanding skin aging at the molecular level.
April 2024 in “Human genomics” Identified genes linked to male-pattern baldness may help develop new treatments.
466 citations,
June 2009 in “Experimental dermatology” We now understand more about what causes acne and this could lead to better, more personalized treatments.
8 citations,
January 2023 in “RSC Advances” Carbon dots show promise for tissue repair and growth but need more research to solve current challenges.
August 2022 in “Metabolites” Different types of skin on mice have unique chemical profiles related to how they grow and react to stress.
July 2022 in “Biomedicines” 4-Aminopyridine improves skin wound healing and tissue regeneration by increasing cell growth and promoting nerve repair.
10 citations,
September 2022 in “Journal of Biophotonics” Blue light therapy is safe for skin and may protect against UV radiation.