research Stem Cells Supporting Other Stem Cells
Stem cells can help other stem cells by producing supportive factors.
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research Building and Maintaining the Skin
Three types of stem cells help maintain and repair skin, responding to health and environmental changes.
research Any Route for Melanoblasts to Colonize the Skin
Melanoblasts migrate to the skin using various pathways, and understanding this process could help with skin disease research.
research Niche Required for Inducing Quiescent Stem Cells
A special environment is needed to fully activate sleeping stem cells.
research Chloracne: Histopathologic Findings in One Case
Tiny infundibular cysts are the main lesions in chloracne, not comedones.
research Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation, and Pigmentation Revealed by Molecular Profiling
ILK is essential for skin development, pigmentation, and healing.
research Platelet-Rich Plasma in Dermatology: Cellular and Molecular Mechanisms of Action
PRP therapy helps skin heal and improve by promoting cell growth and repair.
research Neurobiology, Stem Cell Biology, and Immunology: An Emerging Triad for Understanding Tissue Homeostasis and Repair
The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.
research Narrow-Band Ultraviolet B Phototherapy in Vitiligo
NB-UVB phototherapy is an effective and safe treatment for vitiligo, especially on hands and feet, and can be improved with tacrolimus.
research Understanding Cancer Cells of Origin in Cutaneous Tumors
The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.
research Cell of Origin Contributes to Melanoma Diversity
Different types of stem cells in the skin contribute to the variety of melanoma forms.
research Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
research Montagna Symposium 2015: Harnessing Stem Cells to Reveal Novel Skin Biology and Disease Treatments
The symposium showed that stem cells are key for understanding and treating skin diseases and for developing new skin models and therapies.
research Proceedings of the Heinz Maurer-Symposium: Review and Preview in Science for Healthy Skin, June 28, 2014, Jakobsberg, Boppard, Germany
The symposium concluded that environmental factors significantly contribute to skin aging.
research Viewpoint 1
Understanding skin patterns can help us learn about skin diseases and their treatments.
research News in Brief
Researchers found potential new targets for treating melanoma and nonmelanoma skin cancers, and identified a possible cause and treatment for male pattern baldness and eczema.
research Field Melanin Mapping of the Hairless Scalp
The study found a specific pattern of uneven melanin distribution on balding scalps that could help understand skin diseases caused by light exposure.
research Applications of Human Pluripotent Stem Cell-Derived Skin Organoids in Dermatology
Skin organoids from stem cells can help study and treat skin issues but face some challenges.
research Models for Skin Cancer
The document discussed the three most common types of skin cancer: malignant melanoma, basal cell carcinoma (BCC), and squamous cell carcinoma (SCC). Malignant melanoma, originating from melanocytes, was noted as the most lethal. BCC, the most common cancer, was debated to potentially arise from hair follicle keratinocytes and was associated with mutations in the sonic hedgehog (SHH) pathway, suggesting a link to failed organogenesis. SCC, also arising from keratinocytes, was described as more aggressive than BCC, with the potential to form lethal metastases, unlike BCC, which rarely metastasizes. The document also covered the use of in vivo and in vitro models for studying these skin cancers.
research Immunology of the Human Nail Apparatus: The Nail Matrix Is a Site of Relative Immune Privilege
The nail matrix has a reduced immune response, protecting it from autoimmunity.
research The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle
The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.
research Immune Modulation of Hair Follicle Regeneration
Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
research Immunopathology of the Human Hair Follicle
The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.
research In Vitro Mesenchymal–Epithelial Interaction Facilitates De Novo Hair Follicle Formation
Adult skin cells can be used to create new hair in a lab.
research Human Hair Follicle: Reservoir Function and Selective Targeting
The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
research Regulation of Hair Follicle Development by Exosomes Derived from Dermal Papilla Cells
Exosomes from dermal papilla cells can help grow hair and might treat hair loss.
research Bone Morphogenetic Protein Signaling Regulates Postnatal Hair Follicle Differentiation and Cycling
Blocking BMP signaling causes hair loss and disrupts hair growth cycles.
research The Potential of Nestin-Expressing Hair Follicle Stem Cells in Regenerative Medicine
Hair follicle stem cells could help repair nerves and avoid ethical issues linked to embryonic stem cells.
research The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics
Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
research Keratin Formation in the Hair Follicle
Keratin fibrils in hair form and stop growing at specific points in the follicle.