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Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

The document concluded that more research is needed to find the best treatment for Frontal fibrosing alopecia.

Adding human blood vessel cells to hair follicle germs may improve hair growth and quality.

Vitamin D receptor helps control hair growth and could be used to treat certain skin tumors.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

A form of vitamin E promotes hair growth by activating a specific skin pathway.

Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.

Gamma rays did not change hair follicle density but increased white and hypopigmented hairs in mice.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.

Blood-derived CD34+ cells speed up healing, reduce scarring, and regrow hair in skin wounds.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

Newly found stem cells in horse hooves show promise for treating a hoof disease called laminitis.

PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.

Skin stem cells can help improve skin repair and regeneration.

Notch signaling is essential for healthy skin and hair follicle maintenance.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.

Hair follicle stem cells help skin heal and grow during stretching.

Dermal stem cells help regenerate hair follicles and heal skin wounds.

A new method using a microfluidic device can prepare hair follicle germs efficiently for potential use in hair loss treatments.

Neurohormones help control skin health and could treat skin disorders.

Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.

Hair growth and development are controlled by specific signaling pathways.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.

Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.