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Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Surface Plasmon Resonance is a useful tool for studying protein interactions and has potential for future technological advancements.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Male skin gets drier and more alkaline as it ages, which may need different skincare than women's skin.

Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.

Behavioral dermatology treats skin problems by considering both emotional and physical factors.

Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Baricitinib for severe alopecia areata is generally safe, with common side effects like infections and acne, and low rates of serious complications.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

Microneedling is a safe and effective way to improve various skin conditions with minimal side effects.

Some medications for bladder problems can cause memory issues or mood changes, and doctors should monitor these side effects.

Manage side effects of hepatitis C treatment with dose changes and medications, which may improve patient adherence and treatment success.

Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.

High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.

New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

Akt2 protein is essential for normal cell division in early mouse embryos.

Minoxidil dissolves better in propylene glycol and water as temperature and propylene glycol amount increase.

Chemical exposure may contribute to the rise in atopic diseases and needs more research.

A woman with a rare autoimmune disorder had a blister on her eye and unique immune reaction, which was effectively treated with medication.

Finding new uses for existing drugs is promising and can lead to safer, more effective medicines.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Traditional knowledge of edible oil-producing plants in Sinja Valley is declining due to outmigration and sociocultural changes.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.