research Perspectives on Dermatopathology
Dermatopathology has made significant progress but many skin diseases remain incurable, requiring ongoing research.
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research HDAC6-Dependent Deacetylation of NGF Dictates Its Ubiquitination and Maintains Primordial Follicle Dormancy
HDAC6 helps keep ovarian follicles dormant, extending female fertility.
research Application of Metal Organic Frameworks-Based Functional Composite Scaffolds in Tissue Engineering
Metal organic frameworks-based scaffolds show promise for tissue repair due to their unique properties.
research Myotonic Dystrophy Type 1: Enhancing Patient Management Through Genetic and Multisystem Studies
There is no cure for myotonic dystrophy type 1, so treatment focuses on managing symptoms and complications.
research Tackling Underrepresentation to Aid Understanding of Parkinson’s Disease: Progress and Further Opportunities
Addressing underrepresentation in Parkinson's research is crucial for better treatments and understanding.
research Inherited Epidermolysis Bullosa: A Clinical Case
A 37-year-old male with severe skin and internal issues has a rare inherited skin condition called dystrophic epidermolysis bullosa.
research Structural and Functional Studies of L-PGDS and SMPDL3A Enzymes in Lipid Signaling Family
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
research Chemicals and Stem Cells in the Promotion of Regeneration
Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.
research Stromal Cells of the Human Postmenopausal Ovary Display a Distinctive Biochemical and Molecular Phenotype
Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.
research Problems of Creating Scientific Ideas About World Development
Continuous research and innovative strategies are essential for sustainable development.
research Proceedings of the III International Scientific and Practical Conference
The conference emphasized innovative solutions for global challenges, including disaster architecture, education, health, and economic impacts.
research Repurposing of Linagliptin and Similar FDA Approved Drugs as Antidiabetic Agents
Pranlukast and mirabegron may work as new diabetes drugs.
research Capillaroscopic Patterns in Patients with Systemic Sclerosis, Psoriasis, and Alopecia and Their Correlations with Serum Concentrations of Several Angiogenic Markers
Blood vessel patterns in skin diseases relate to certain blood markers in systemic sclerosis but not in psoriasis or psoriatic arthritis, and may indicate circulation issues in alopecia.
research Gonads
The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
research Self-Consistent Field Theory for the Interactions Between Keratin Intermediate Filaments
Keratin filaments' elasticity is influenced by their terminal domains and surrounding medium.
research Trichoscopy Patterns in Alopecia Areata: A Systematic Review and Meta-Analysis
Yellow dots and short vellus hairs are the most common signs of Alopecia Areata (AA), and trichoscopy can help diagnose AA and track treatment progress.
research The Susceptibility of Disulfide Bonds to Modification in Keratin Fibers Undergoing Tensile Stress
Disulfide bonds in keratin fibers break more easily under stress, especially when wet, affecting fiber strength.
research Multipotent Nestin-Positive Stem Cells Reside in the Stroma of Human Eccrine and Apocrine Sweat Glands and Can Be Propagated Robustly In Vitro
Human sweat glands have a type of stem cell that can grow well and turn into different cell types.
research Read-Through for Nonsense Mutations in Type XVII Collagen-Deficient Junctional Epidermolysis Bullosa
A new therapy for a skin blistering condition has not been developed yet.
research Laccase-Catalyzed Poly(Tyrosine) Grafting Improves The Performance Of Wool
Using laccase to add poly(tyrosine) to wool makes it less likely to shrink and stronger.
research LGR5 Is a Marker of Poor Prognosis in Glioblastoma and Is Required for Survival of Brain Cancer Stem-Like Cells
High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.
research FLCN, A Novel Autophagy Component, Interacts With GABARAP And Is Regulated By ULK1 Phosphorylation
The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
research Stem Cell Therapy for Burns: The Story So Far
Stem cell therapy shows promise in improving burn wound healing.
research Epidermolysis Bullosa Simplex: A Paradigm for Disorders of Tissue Fragility
Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.
research Scarless Wound Healing: Transitioning from Fetal Research to Regenerative Healing
Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.
research Histochemical and Immunohistochemical Markers for Human Eccrine and Apocrine Sweat Glands: An Aid for Histopathologic Differentiation of Sweat Gland Tumors
Markers help differentiate between apocrine and eccrine sweat glands to identify sweat gland tumors.
research Keratin Intermediate Filaments in the Colon: Guardians of Epithelial Homeostasis
Keratin proteins are essential for keeping the cells in the human colon healthy and stable.
research Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution, And Tumor-Initiating Cells
Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.
research Transcriptome Meta-Analysis Confirms the Hidradenitis Suppurativa Pathogenic Triad: Upregulated Inflammation, Altered Epithelial Organization, and Dysregulated Metabolic Signaling
The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.