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Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.

The study found key factors in the cause of hidradenitis suppurativa, its link to other diseases, and identified existing drugs that could potentially treat it.

GLI1 might protect against the start of skin cancer and is not linked to cancer severity.

Cannabinoids might help treat skin problems but more research is needed to be sure.

Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.

Different treatments for Hidradenitis suppurativa range from antibiotics and hormonal therapies to surgery, depending on severity.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Gendered social factors, not just biology, contribute to sex differences in adverse drug events.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

There is no gold standard treatment for hidradenitis suppurativa due to insufficient evidence.

Lrig1 could be a marker for advanced sebaceous carcinoma.

Epidermal stem cells show promise for treating orthopedic injuries and diseases.

Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.

Cobalt is important for health but too much or too little can cause health problems, and its environmental buildup is a concern.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Public interest in finasteride's sexual side effects has significantly increased.

Dabrafenib was effective and well tolerated in treating thyroid cancer with a specific mutation.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

Tiny vesicles from stem cells could be a new treatment for healing wounds.

Antiandrogen therapy for hidradenitis suppurativa lacks strong evidence and needs more research.

Brothers of women with PCOS tend to have higher levels of a hormone called DHEAS, indicating a possible genetic link.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.

Nanoparticles added to natural materials like cellulose and collagen can improve cell growth and wound healing, but more testing is needed to ensure they're safe and effective.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

MAIT cells may help fight COVID-19 but also contribute to severe inflammation.

COVID-19 can cause skin problems in children.

Your skin is like an ecosystem, with its own community of microbes and substances that interact and affect its health.