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This study found that Th17 lymphocytes may play a more crucial role than cytotoxic T cells in the development of alopecia areata due to their infiltration around the hair bulb/bulge, which exacerbates hair loss as histopathological grade worsens.

This study found that in chronic alopecia areata, increased IL-17 expression and CD8+CD49a-Trm cell infiltration in hair follicles were associated with more severe histopathologic gradings, while Foxp3+mTreg infiltration decreased.

This study found that in alopecia areata, hair bulbs are blocked in an early growth stage due to impaired metabolic function in the surrounding connective tissue, hindering hair growth.

This review discusses the role of immune privilege collapse in the pathogenesis of alopecia areata, emphasizing the potential for therapeutic manipulation of hair bulb immune privilege to offer new treatment options, and reports no new results.

This article discusses the diagnostic methods for differentiating alopecia areata from similar hair loss conditions and emphasizes the importance of accurate diagnosis, but it reports no new research findings.

This study found that prolactin and its receptor are expressed in the murine hair follicle epithelium, influencing hair cycle phases by down-regulating keratinocyte proliferation during anagen and inducing premature catagen.

This study found that Imaging Mass Cytometry effectively visualizes multiple biomarkers in alopecia areata, enhancing analysis of immune cell and tissue interactions in hair pathology.

This study suggests that IL-17 may play a more significant role than IFN-γ in the pathogenesis of chronic alopecia areata, with increasing severity linked to Th17 lymphocytes and cytotoxic T lymphocyte infiltration.

In this study, 25% of CCHCR1-deficient mice exposed to stress developed hair loss similar to human alopecia areata, suggesting CCHCR1 is a susceptibility gene for the disease.

This case report emphasizes that lipedematous scalp and lipedematous alopecia are not distinct diseases, highlighting the need to consider reversible causes of alopecia for effective treatment.

This study found that plasmacytoid dendritic cells are central to the pathogenesis of alopecia areata, suggesting they may help differentiate it from trichotillomania and androgenetic alopecia.

This text resembles an instructional or informational template for journal subscribers and authors, not a research abstract reporting specific findings.

COVID-19 vaccines have been linked to an increase in hair loss conditions.

In this study, researchers found two distinct stem cell reservoirs in human hair follicles that require mesenchymal cells for stem cell proliferation.

Trichohyalin in hair can trigger immune attacks in alopecia areata.

This case report highlights that lipedematous scalp and alopecia areata may coexist and that precise diagnosis requires histopathologic examination.

This study found that alopecia areata is linked to genetic factors, specifically HLA haplotypes on chromosome 6, and involves immune privilege collapse at hair follicles which is mediated by the JAK-STAT pathway and pro-inflammatory cytokines like IFN-γ.

This study reported that heterozygosity for FHIT affects mice's susceptibility to spontaneous alopecia areata and to certain preneoplastic lesions induced by benzo[a]pyrene, but does not change how they respond to budesonide and N-acetyl-L-cysteine.

The study demonstrated that bulge stem cells from rat vibrissa follicles respond to adult dermal papilla signals, inducing hair bulb formation and regenerating hair structures in vivo.

This study found that the proprietary aptamer TAGX-0003 significantly inhibited IFNγ-induced effects in pre-clinical human models of alopecia areata, promoting hair regrowth and potentially preventing disease relapse.

This study found that low fluence photoepilation with intense pulsed light targets the pigmented area of hair follicles, causing temporary hair loss by inducing a catagen-like state without severe follicle damage.

This article reviews the biological and physical principles of laser hair removal and reports that current laser systems do not consistently achieve permanent hair follicle destruction across treated areas.

This review highlights that alopecia areata is characterized by three immune endotypes, and while JAK inhibitors offer temporary control, upcoming multi-omics diagnostics and immune reprogramming strategies may achieve longer-lasting remission, according to this analysis.

This study observed that hirsute females displayed increased S-phase hair bulb cells and decreased G0/1-phase cells compared to healthy females, with a strong correlation between S-phase percentages and DHEA-S levels.

This study found that daily injections of basic and acidic fibroblast growth factor in newborn mice significantly delayed hair follicle development within the treatment area, while epidermal growth factor affected the entire body coat and caused skin hyperkeratinization.

This study reports that the peptide GPIGS, found in Bacillus sp. M18 conditioned medium, may promote hair growth through the PI-3K/Akt pathway and accelerate hair regrowth in mice.

Early stage bald spots are linked to skin inflammation and damage to the upper part of the hair follicle.

This study observed that nestin-positive, K15-negative cells in hair follicles may play a crucial role in hair follicle regeneration in patients with alopecia areata.

The study observed that in women, the number of hair follicles with an internal root sheath decreases with age in the parietal region, also hinting at a reduction in hair follicle and shaft width.

In this study, LHX2 and SOX9 were found to mark distinct epithelial progenitor cell populations within human hair follicles, suggesting roles in maintaining the hair follicle epithelium.