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Certain histamine receptors (H2R, H3R, H4R) have unique roles in treating skin diseases, with H2R helping with chronic urticaria and other conditions, H3R providing pain relief and allergy benefits, and H4R reducing inflammation and itchiness.

New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.

Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Physical activity, height, and smoking affect prostate cancer risk.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.

Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.

Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.

Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.

Male hormones worsen kidney transplant damage, but blocking them helps.

Dieckol from Ecklonia cava may help hair growth and could be a potential hair loss treatment.

Researchers created a skin patch that delivers two drugs for treating enlarged prostate, which may improve patient use and dosage control.

Stinging nettle has compounds that help with joint pain, arthritis, and prostate issues.

Custom software found that common allergy drugs might have new uses for various conditions and could improve survival in some cancers.

The document concludes that specific methods for making diazine-based drugs can lead to high yields and are important for creating effective treatments for various diseases.

Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.

New insights into the causes and treatments for the autoimmune hair loss condition Alopecia areata have been made.

Retinoic acid affects male and female muscle energy use and function differently.

Delta-opioid receptors affect skin cell circadian rhythms, possibly impacting wound healing and cancer.

Mutations in certain receptors can cause diseases and offer new treatment options.

Certain gene variants in estrogen receptors are linked to polycystic ovary syndrome, mainly affecting metabolism, in Tunisian women.

The Hairless gene is crucial for healthy skin and hair growth.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.