research HPV8 E6 Induced STAT3 Activation Leads to Hair Follicle Junctional Zone Keratinocyte Stem Cell Proliferation and Expansion in Actinic Keratoses
HPV8 causes hair follicle stem cells to grow, leading to skin lesions.
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research Automated Skin Surface Phenotype for Melanoma Risk Assessment
An automated method accurately assesses melanoma risk using 3D body images to analyze skin traits.
research A Single-Cell RNA Map of Perinatal Developing Mouse Skin
The research mapped gene activity in developing mouse skin and found key markers for skin cell types and changes from fetal to early postnatal stages.
research Reliable and Interpretable Segmentation for Remote Assessment of Atopic Dermatitis Severity Using Digital Images
The improved EczemaNet more reliably and clearly identifies and assesses the severity of atopic dermatitis from photos.
research A Single-Center Retrospective Study Evaluating the Efficacy of Intravenous Methylprednisolone Pulse Therapy for 113 Patients With Alopecia Areata
Intravenous methylprednisolone helped over half of alopecia areata patients regrow hair, but many relapsed.
research Local Injection With Anti-Herpes Simplex Virus Antibodies Protects Against Development of Herpes Simplex Virus-Induced Sweating Disturbance
Injecting anti-herpes antibodies locally can prevent skin lesions and sweating problems caused by herpes simplex virus in mice.
research IKZF1 and IKAROS Overexpression Contributes to the Pathogenesis of Alopecia Areata
Too much IKZF1 and Ikaros protein may cause alopecia areata.
research P120-Catenin Regulates Epidermal Inflammation in a Cadherin-Dependent Manner
p120-catenin helps control skin inflammation by regulating cadherin levels.
research Loss of UBE2N in Keratinocytes Leads to Skin Inflammation and Immune Infiltration Through IRAK1/4-Mediated Processes
Removing UBE2N from skin cells causes inflammation and immune response, which can be lessened with specific inhibitors.
research The Role of Mitochondria in Skin Aging
Mitochondrial dysfunction contributes to skin aging and hair loss.
research Impact of Type 2 Cytokines on the Keratinocytes-Staphylococcus Aureus Interaction
Type 2 cytokines IL-4 and IL-13 increase skin's vulnerability to Staphylococcus aureus, which could be important for treating atopic dermatitis.
research Amelioration of Symptoms of Dry and Eczema-Prone Skin by an Oil-in-Water Emulsion Containing a Combination of Zingiber Officinale Root Extract and CBD with Antioxidative and Anti-Inflammatory Activity In Vitro
An oil-in-water emulsion with CBD and ginger root extract significantly improved symptoms of dry and eczema-prone skin.
research Cyclosporin A Suppresses TGF-Beta2 Expression Via Calcineurin/NFAT Pathway in Human Dermal Papilla Cells
Cyclosporin A, a drug, reduces TGF-β2 expression in skin cells, potentially causing excessive hair growth through a process involving the calcineurin/NFAT pathway.
research Dimethyl Fumarate Ameliorates Delayed Wound Healing Due to IL-36Ra Deficiency Through Inhibition of NET Formation and Oxidative Stress
Dimethyl fumarate speeds up wound healing in IL-36Ra deficient mice by reducing NET formation and oxidative stress.
research Type 2-Mediated Oxidative Reprogramming Promotes Macrophage Transition into Repair Mode for Wound Healing
Type 2 inflammation helps wound healing by switching immune cells to repair mode.
research Primary Cutaneous Diffuse Large B-Cell Lymphoma–Leg Type Masquerading as a Mucocele
An elderly woman's upper lip lump, thought to be a mucocele, was actually a rare type of lymphoma usually found on legs, treated successfully with chemotherapy and radiation.
research Prostacyclin Pathway to Enhance Wound Healing in Diabetic Foot Ulcers
Treprostinil, a drug, can delay wound healing in healthy cells but doesn't affect diabetic foot ulcer cells, suggesting further research could help understand its role in treating these ulcers.
research Fate Tracing of DNA-Damaged Hair Follicle Stem Cells and Their Seno-Differentiation Clearance Out of the Niche
Damaged hair follicle stem cells may leave the skin to help maintain youthfulness.
research Cross-Comparison of Inflammatory Skin Disease Transcriptomics Identifies PTEN as a Pathogenic Disease Classifier in Cutaneous Lupus Erythematosus
PTEN was identified as a specific marker for the skin disease cutaneous lupus erythematosus, and it helps increase the expression of harmful type I interferons.
research Prospective Study of the Metabolic Effects of Tumescent Liposuction
Tumescent liposuction reduces waist and hip size but doesn't significantly change metabolic markers, though it may slightly improve blood pressure and certain protein levels.
research Automated Assessment of Tumor Infiltrating Lymphocytes Informs Mortality in Thin Melanoma
An automated system can predict death risk in thin melanoma by analyzing immune cells.
research Humoral Immune Response to COVID-19 Vaccination in Psoriasis Patients on Biologic Therapy Is Impaired Compared to Healthy Controls
Psoriasis patients on biologic therapy have a weaker immune response to COVID-19 vaccination than healthy people.
research Involvement of Mast Cells and CB1 in the Pathogenesis of IgA Vasculitis
Mast cells and the CB1 receptor may be key in causing IgA vasculitis.
research Effect of Hydroxypropyl Methylcellulose in Release Profile of Air Fresheners Gel Using Carrageenan and HPMC
The F2 Emulgel with Tridax procumbens extract showed good physical properties and antimicrobial effectiveness for wound healing.
research In Vivo Reprogramming of Wound-Resident Cells Generates Skin with Hair
Scientists can now create skin with hair by reprogramming cells in wounds.
research Comparative Histopathological Analyses of Non-Scarring Alopecia in Systemic Lupus Erythematosus Patients in Lagos, Nigeria
The main difference in hair loss for lupus patients is smaller and fewer sebaceous glands.
research Acute and Chronic Telogen Effluvium
Hair shedding that lasts over 6 months may need a closer look, but often just reassurance is enough.
research Hair From Sexually Active Bucks Activates Olfactory Inputs But Does Not Trigger Early First Ovulation in Prepubescent Does
Male goat smell increases reaction in young female goats' noses but doesn't cause them to start puberty early.
research Clinical Spectrum And Immunological Profile Of Patients With Mixed Connective Tissue Disease Presenting In A Tertiary Care Hospital
Early treatment of mixed connective tissue disease is crucial to prevent severe autoimmune conditions.
research Hipsc-Derived Skin Organoids as Tools for Disease Modelling: Characterization of the Epidermal-Dermal Junction
Human-induced stem cell-created skin models can help understand skin diseases by studying the skin's layers.