research Melasma and Endocrine Disorders
Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.
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research Glycine Inhibits Melanogenesis in Vitro and Causes Hypopigmentation in Vivo
Glycine reduces skin pigmentation by lowering melanin production.
research Formulation of Hair Tonic with Ethanol Extract of Hibiscus Leaves (Hibiscus tiliaceous L.) for Hair Growth in Guinea Pigs (Cavia parcellus)
Hibiscus leaf extract in hair tonic promotes hair growth effectively.
research Formulation of Hair Tonic from Ethanol Extract of Sea Hibiscus (Hibiscus Tiliaceus L.) Leaves in Promoting Hair Growth on Guinea Pigs (Cavia Porcellus)
Sea hibiscus leaf extract at 30% concentration in a hair tonic significantly increased hair growth in guinea pigs.
research Interspecies Variations in Response to Topical Application of Selected Zinc Compounds
Different zinc compounds cause varying levels of skin irritation in animals.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Reversing Gray Hair: Inspiring the Development of New Therapies Through Research on Hair Pigmentation and Repigmentation Progress
Gray hair can potentially be reversed, leading to new treatments.
research Oral Administration of TrkB Agonist, 7,8-Dihydroxyflavone Regenerates Hair Cells and Restores Function after Gentamicin-Induced Vestibular Injury in Guinea Pig
research The Transdermal Inhibition of Melanogenesis by a Cell-Membrane-Permeable Peptide Delivery System Based on Poly-Arginine
A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.
research Severe Kerion Celsi Due to Trichophyton Mentagrophytes: A Case Report
Tinea capitis needs systemic treatment to avoid severe outcomes.
research Androgen-Induced Norepinephrine Release in Male Accessory Sex Organ Smooth Muscle Growth and Differentiation
Androgens increase norepinephrine release, promoting smooth muscle growth in male sex organs, which may contribute to benign prostatic hypertrophy.
research Olorofim Effectively Eradicates Dermatophytes In Vitro and In Vivo
Olorofim effectively treats fungal skin infections.
research A Study of the Differentiation Products of the Hair Follicle Cells with the Electron Microscope
Hair follicle cells become four types: medulla, cortex, cuticle, and inner root sheath.
research Rodent Models in Placental Research: Implications for Fetal Origins of Adult Disease
Using rodents for research shows that health problems in the womb can cause diseases later in life.
research Ototoxicity of Common Topical Antimycotic Preparations
Clotrimazole, miconazole, and tolnaftate are likely safe, but gentian violet is risky.
research Acute Dermal and Ocular Irritation Testing of Rice Bran Supercritical CO2 Extract (RB-SCE) and 0.5% RB-SCE Essence Product
Rice bran extract caused moderate skin irritation but no eye irritation, while a diluted essence was not irritating to skin and only slightly to guinea pigs.
research Zinc Deficiency Triggers Hearing Loss by Reducing Ribbon Synapses of Inner Hair Cells in CBA/N Mice
Lack of zinc can cause hearing loss by damaging important parts of inner ear cells in mice.
research Comparison of the Effects of the K+-Channel Openers Cromakalim and Minoxidil Sulphate on Vascular Smooth Muscle
Cromakalim relaxes various blood vessels, while minoxidil sulphate is more selective; they likely act on different potassium channels.
research Trends in Human Hair Growth and Alopecia Research
The book reveals diverse patterns of hair growth in different species and advancements in hair and alopecia research.
research Trichohyalin, an Intermediate Filament-Associated Protein of the Hair Follicle
Trichohyalin is a protein in hair follicles that helps form hair filaments.
research Contributions of Experimental Animal Research to Dermatology
Animal research has greatly advanced dermatology.
research Production of Ultraviolet-Light-Induced Skin Erythema in the Hairless Rat: A Comparison with the Haired Rat in Screening for Anti-Inflammatory Drugs
Hairless rats are good for testing anti-inflammatory drugs, similar to haired rats, without needing to remove fur.
research Development of Gene Therapy for Inner Ear Disease: Using Bilateral Vestibular Hypofunction as a Vehicle for Translational Research
Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.
research Toxicological Studies on Procyanidin B-2 for External Application as a Hair Growing Agent
Procyanidin B-2 is safe to use on skin as a hair growth product.
research Green Hair Discoloration Due to Selenium Sulfide
Selenium sulfide in anti-dandruff shampoos can turn hair green.
research A Sensitive Assay for the Enzyme Activity in Hair Follicles and Epidermis That Catalyzes the Peptidyl-Arginine-Citrulline Post-Translational Modification
A more sensitive assay was developed to detect enzyme activity converting arginine to citrulline in hair follicles.
research Minoxidil Opens Mitochondrial KATP Channels and Confers Cardioprotection
Minoxidil protects heart and improves recovery.
research An Animal Model of Trichloroethylene-Induced Skin Sensitization in BALB/c Mice
Trichloroethylene causes skin inflammation in mice by increasing certain immune proteins.
research Colchicine Therapy for Psoriasis
Sudden weight loss can cause significant hair loss, and using colchicine on the skin for psoriasis may be unsafe.
research Design of an Artificial Skin. IV. Use of Island Graft to Isolate Organ Regeneration from Scar Synthesis and Other Processes Leading to Skin Wound Closure
Island grafts can help study skin regeneration separately from other healing processes.