441 citations
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May 1996 in “Journal of Cell Science” This study found that keratin 19 may be a marker for skin stem cells, helping to characterize these cells in different conditions and potentially explaining variations in healing rates between children and adults.
1 citations
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March 2007 in “Journal of Chinese Integrative Medicine” In this study, Huoxue Bushen Mixture was associated with increased blood vessel formation and VEGF expression in mice hair follicles, suggesting it may enhance hair growth.
46 citations
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December 1992 in “The Journal of Steroid Biochemistry and Molecular Biology” In this study, researchers observed that testicular 17β-hydroxysteroid dehydrogenase deficiency in an inbred Arab population in Israel leads to genital ambiguity at birth and progressive virilization after puberty.
May 2025 in “BMC Genomics” This study found that circ 0020938 suppresses hair follicle stem cell proliferation by interacting with the miR-142-5p/DSG4 axis, which aids in the hair follicle cycle's proper progression.
1 citations
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October 2022 in “Annals of Translational Medicine” This study found that cucurbitacin cream reduced FGF18 levels and accelerated hair follicle transition to the anagen phase in mice, suggesting its potential as a treatment for hair regeneration.
November 2010 in “International Journal of Developmental Neuroscience” 10 citations
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September 2022 in “Animals” This research identified 18 significant SNPs and several candidate genes associated with udder conformation traits in Holstein cattle, providing insights into their genetic architecture.
This study found that type XVII collagen (COL17) regulates interfollicular epidermis proliferation in both neonatal and aged mice through Wnt signaling, suggesting its potential as a target for anti-aging skin strategies.
10 citations
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January 2009 This study suggests that collagen XVIII and its variant endostatin may play a role in regulating Wnt-signaling in hair follicles, affecting wound healing and skeletal development in mice.
11 citations
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June 2019 in “Tissue & Cell” This study indicates that COL17A1 plays a crucial role in the differentiation process of hair-follicle-associated pluripotent stem cells.
August 2025 in “BMC Pregnancy and Childbirth” In this study, prenatal ultrasonography was found to be a valuable tool for screening ectodermal dysplasia during pregnancy, and a new EDA gene variant associated with X-linked hypohidrotic ectodermal dysplasia was identified, aiding in more accurate diagnoses and reproductive decision-making.
This study reported that acupuncture combined with topical Aloe vera and celery gel reduced hair loss from alopecia androgenetica after 28 days of treatment.
October 2019 in “Research Square (Research Square)” This study aims to evaluate the efficacy of the traditional Chinese medicine YH0618 granule for reducing chemotherapy-induced hair loss in breast cancer patients through a double-blind, randomized clinical trial, assessing hair loss progression and improving quality of life markers compared to a placebo.
December 2022 in “American journal of medical genetics. Part A” This case report describes an instance of autosomal recessive uncombable hair syndrome caused by maternal uniparental disomy of chromosome 1.
June 2024 in “Synthetic and systems biotechnology” In this study, researchers identified a collagen fragment, sample-1707, expressed in E. coli, which forms nanofibers and promotes blood clotting, osteoblast differentiation, and skin cell regeneration, making it a promising biomaterial for skin care, with a large-scale production yield of 600 mg/L.
January 2024 in “Doria (University of Helsinki)” This study found that in mouse pancreatic β-cells, the disruption of keratin filaments due to a specific mutation in keratin 18 resulted in altered GLUT2 localization, with less GLUT2 present on the plasma membrane compared to cells with normal keratin.
66 citations
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August 2007 in “Applied and environmental microbiology” This study engineered a bioluminescent yeast strain responsive to androgenic chemicals, demonstrating rapid and sensitive detection suitable for high-throughput screening and environmental monitoring.
31 citations
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February 1997 in “The Journal of Clinical Endocrinology and Metabolism” This study concluded that heterozygosity for CYP21 mutations is associated with higher mean and free testosterone levels in women but does not significantly increase their risk of developing clinically evident hyperandrogenism.
13 citations
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February 2023 in “Aging” This study found that exosomes from hair follicle mesenchymal stem cells overexpressing lncRNA H19 promoted diabetic skin wound healing by enhancing cell proliferation, migration, and reducing pyroptosis.
59 citations
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November 2002 in “Pediatric Dermatology” This article describes a case of dyschromatosis universalis in a young Saudi Arabian girl, discussing similar cases reported outside the Far East where the condition was initially identified, but provides no new research findings.
9 citations
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June 2016 in “The Cerebellum”
This study successfully established a functionally stable immortalized sheep granulosa cell line (GCs-SV40T-GFP) that can passaged up to 50 generations, maintaining morphological stability and estradiol secretion, offering a valuable model for research into animal reproductive function and hormone regulation.
January 2010 in “Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai” This study found that Huoxue Bushen Mixture increased VEGF expression and the proliferation of dermal papilla cells, suggesting it may promote hair growth compared to control treatments in rats.
88 citations
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June 2000 in “Journal of Investigative Dermatology” Keratin 17 is important for hair and nail structure and affects pachyonychia congenita symptoms.
January 2015 in “CHINESE JOURNAL OF ANALYTICAL CHEMISTRY (CHINESE VERSION)” This study developed a rapid and reliable ultra high performance liquid chromatography method for analyzing 17 key ingredients in hair growth cosmetics.
7 citations
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February 2015 in “Journal of comparative pathology” This study observed that NSG-hu-BLT mice developed graft-versus-host disease characterized by CD8+ T lymphocyte-related cell death in the skin and liver, which may affect their utility in other research areas.
October 1984 in “Kidney international” This case report describes a 23-year-old woman with a history of ambiguous genitalia and complex medical conditions, including a pelvic mass and hirsutism, observed from childhood to adulthood.
7 citations
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January 2023 in “Journal of Animal Science” This study found that the miRNA chi-miR-877-3p affects hair follicle cycles in Jiangnan cashmere goats by regulating IGFBP5 gene expression and cell proliferation.
4 citations
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March 2010 in “International Journal of Oral Science” This study concluded that the Chinese herbal medicine Xianhuayin effectively reversed DMBA-induced premalignant lesions in the buccal pouch of golden hamsters.
July 2026 in “Journal of the American Academy of Dermatology”