Cerebellar Changes in Guinea Pig Offspring Following Suppression of Neurosteroid Synthesis During Late Gestation
June 2016
in “
The Cerebellum
”
Research cited in this study
4 / 4 resultsresearch Sex-Dependent Effect of a Low Neurosteroid Environment and Intrauterine Growth Restriction on Fetal Guinea Pig Brain Development
This study found that decreased allopregnanolone levels through inhibition or intrauterine growth restriction in guinea pigs were linked to altered brain development markers, suggesting a role for neurosteroids in fetal brain protection and development.
research Role of Neurosteroids in Regulating Cell Death and Proliferation in the Late Gestation Fetal Brain
This study found that inhibiting allopregnanolone synthesis in late gestation fetal sheep increased apoptosis and dead cell count in the hippocampus and cerebellum, effects that were mitigated by alfaxalone co-infusion.
research Inhibition of Neurosteroid Synthesis Increases Asphyxia-Induced Brain Injury in the Late Gestation Fetal Sheep
This study found that treatment with finasteride in fetal sheep reduced the protective neurosteroid allopregnanolone, leading to increased cell death in the hippocampus following induced fetal asphyxia.
research The Biological Actions of Dehydroepiandrosterone Involve Multiple Receptors
This review discusses how dehydroepiandrosterone (DHEA) may exert its biological effects through multiple receptors and reports no new clinical results.